Nanog Protein
Quick Overview for Nanog Protein (ABIN935689)
Target
See all Nanog (NANOG) ProteinsProtein Type
Origin
Source
Purity
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Sequence
- SVDPACPQSL PCFEASDCKE SSPMPVICGP EENYPSLQMS SAEMPHTETV SPLPSSMDLL IQDSPDSSTS PKGKQPTSAE NSVAKKEDKV PVKKQKTRTV FSSTQLCVLN DRFQRQKYLS LQQMQELSNI LNLSYKQVKT WFQNQRMKSK RWQKNNWPKN SNGVTQKASA PTYPSLYSSY HQGCLVNPTG NLPMWSNQTW NNSTWSNQTQ NIQSWSNHSW NTQTWCTQSW NNQAWNSPFY NCGEESLQSC MQFQPNSPAS DLEAALEAAG EGLNVIQQTT RYFSTPQTMD LFLNYSMNMQ PEDV
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Characteristics
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Purified recombinant Human Nanog protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Nanog Homeobox (NANOG) (AA 1-305) protein (His tag)
custom-made NANOG Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nanog Homeobox (NANOG) (AA 1-305) protein (His tag)custom-made NANOG Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Nanog Homeobox (NANOG) (AA 2-305) protein (His tag)NANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Nanog Homeobox (NANOG) (AA 1-305) proteinNANOG Origin: Human Host: Escherichia coli (E. coli) > 90 % by SDS - PAGE SDS
Nanog Homeobox (NANOG) (AA 1-154) protein (His tag)NANOG Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Alternative Name
- Nanog
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Background
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Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which maintains pluripotency and self renewal via a STAT3 independent pathway. Recombinant human.
Alternative Names: Homeobox protein NANOG protein, hNanog protein, Embryonic stem cell specific homeobox protein protein, ENK protein, Homeobox transcription factor Nanog protein -
Molecular Weight
- 34.5 kDa
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Pathways
- Stem Cell Maintenance
Target
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