NRN1 Protein
Quick Overview for NRN1 Protein (ABIN935695)
Target
See all NRN1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MAGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN
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Characteristics
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Purified recombinant Human Neuritin protein
Expression System: E.coli
Bioactivity: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- NRN1 (Neuritin 1 (NRN1))
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Alternative Name
- Neuritin
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Background
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Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation.
Alternative Names: CPG15 protein, NRN1 protein -
Molecular Weight
- 9.7 kDa
Target
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