Resistin Protein (RETN)
Quick Overview for Resistin Protein (RETN) (ABIN935761)
Target
See all Resistin (RETN) ProteinsProtein Type
Origin
Source
Purity
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Sequence
- SSMPLCPIDE AIDKKIKQDF NSLFPNAIKN IGLNCWTVSS RGKLASCPEG TAVLSCSCGS ACGSWDIREE KVCHCQCARI DWTAARCCKL QVAS
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Characteristics
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Purified recombinant Human Resistin protein
Expression System: E.coli -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 g/mL.
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Buffer
- Lyophilized from 20 mM tris, pH 8.0.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Resistin (RETN)
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Alternative Name
- Resistin
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Background
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Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes.
Alternative Names: Adipose tissue-specific secretory factor protein, FIZZ3 protein, ADSF protein -
Molecular Weight
- 20.2 kDa
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Target
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