CXCL12 Protein
Quick Overview for CXCL12 Protein (ABIN935781)
Target
See all CXCL12 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
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Characteristics
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Purified recombinant Mouse SDF1 alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration of 50-100 ng/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) (Active) protein (His tag,GST tag)
CXCL12 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (Active) proteinCXCL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) protein (His-IF2DI Tag)CXCL12 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) protein (His tag)CXCL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-93) protein (His-IF2DI Tag)CXCL12 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 1-89) protein (GST tag)CXCL12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 24-89) (Active) protein (Biotin)CXCL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE FACS, CMA Active
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) proteinCXCL12 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) proteinCXCL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
Chemokine (C-X-C Motif) Ligand 12 (CXCL12) proteinCXCL12 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in Sterile water to 0.1-1.0 mg/mL. Allow to set for at least 30 minutes.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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Alternative Name
- SDF1 alpha
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Background
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SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.
Alternative Names: SDF-1 alpha protein, PBSF protein, SDF1 alpha, SDF 1 alpha protein, SDF-1 alpha, SDF 1 alpha, SDF-1 alpha protein, CXCL12 protein, Stromal-Cell Derived Factor-1 protein -
Molecular Weight
- 7.9 kDa
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Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
Target
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