CXCL12 Protein

Catalog No. ABIN935803

Recombinant CXCL12 protein expressed in Escherichia coli (E. coli).

Quick Overview for CXCL12 Protein (ABIN935803)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK

Characteristics: Purified recombinant Human SDF1 alpha protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50.0-100.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Alternative Name: SDF1 alpha

Background: SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.
Alternative Names: SDF-1 alpha protein, CXCL12 protein, Stromal-Cell Derived Factor-1 protein, SDF-1 alpha protein, SDF1 alpha, PBSF protein, SDF-1 alpha, SDF 1 alpha protein, SDF 1 alpha

Molecular Weight: 7.9 kDa

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling