TNFSF15 Protein
-
- Target See all TNFSF15 Proteins
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Sequence
- QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL
- Characteristics
-
Purified recombinant Human TL1 A protein
Expression System: E.coli
Bioactivity: Determined by its ability to stimulate IFN-gamma production by human PBMC using a concentration range of 10.0-100.0 ng/mL. Note: Results may vary with PBMC donors. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TNFSF15 Protein
-
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 91-251), (Trimer) protein (His-DYKDDDDK Tag)
TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag,Biotin)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (His tag)custom-made TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-252) protein (His tag)custom-made TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (His-Avi Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 61-252) protein (Fc Tag)TNFSF15 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His-DYKDDDDK-Strep II Tag)TNFSF15 Origin: Human Host: HEK-293T Cells Recombinant ELISA, SDS, WB, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) protein (His tag)TNFSF15 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 1-251) protein (GST tag)TNFSF15 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (AA 72-251) (Active) protein (His tag)TNFSF15 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- Target
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Alternative Name
- TL1A (TNFSF15 Products)
- Background
-
TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NF kb activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6.
Alternative Names: VEGI protein, TNFSF15 protein, TL-1A protein, TLA 1, TL1A, TLA 1 protein, TLA-1, TLA-1 protein - Molecular Weight
- 22.0 kDa
- Pathways
- Positive Regulation of Endopeptidase Activity, Autophagy
-
