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TIFF1 (Active) Protein

This Recombinant protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN935870

Quick Overview for TIFF1 (Active) Protein (ABIN935870)

Target

TIFF1

Protein Type

Recombinant

Biological Activity

Active

Origin

Human

Source

Escherichia coli (E. coli)

Purity

> 98 % pure
  • Sequence

    EAQTETCTVA PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF

    Characteristics

    Purified recombinant Human TIFF1 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human MCF-7 cells using a concentration 5-10 µg/mL.

    Endotoxin Level

    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Supplied as a lyophilized powder.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target

    TIFF1

    Background

    The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene. Recombinant human TFF1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
    Alternative Names: BCEI protein, TIFF-1 protein, HP1.A protein, pS2 protein protein, PNR2 protein, TIFF1, TIFF-1, Breast Cancer Estrogen-Inducible protein protein, TIFF 1, TIFF-1 protein, TIFF 1 protein

    Molecular Weight

    6.7 kDa
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