TIFF3 (Active) Protein

Catalog No. ABIN935871

This Recombinant protein is expressed in Escherichia coli (E. coli).

Quick Overview for TIFF3 (Active) Protein (ABIN935871)

Target: TIFF3

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

Characteristics: Purified recombinant Human TIFF3 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract human MCF-7 cells using a concentration range of 1.0-10.0 µg/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: TIFF3

Background: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation.
Alternative Names: TIFF-3 protein, TIFF 3, Intestinal trefoil factor protein, TIFF-3, Trefoil Factor 3 protein, ITF protein, TIFF-3 protein, TFI protein, TIFF 3 protein, TIFF3

Molecular Weight: 13.2 kDa