VEGFE Protein
Quick Overview for VEGFE Protein (ABIN935896)
Target
Protein Type
Origin
Source
Purity
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Characteristics
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Purified recombinant VEGFE protein (Orf virus)
Expression System: E.coli
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in PBS or water to a concentration not lower than 100 µg/mL, pH 7.4.
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- VEGFE
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Target Type
- Viral Protein
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Background
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Like VEGFA, VEGFE was found to bind with high affinity to VEGF receptor-2 (KDR) resulting in receptor autophosphorylation, whilst in contrast to VEGFA, VEGFE can not bind to VEGF receptor-1 (Flt-1). Furthermore VEGFE can also not bind to VEGF receptor-3 (FLT-4). Therefore VEGFE is a potent angiogenic factor selectively binding to VEGF receptor -2/KDR.
Alternative Names: VEGF E protein, Vascular Endothelial Growth Factor-E protein PDGF-C protein, SCDGF protein, Spinal cord-derived growth factor protein, VEGF-E protein, Fallotein protein, SCDGF protein, PDGFC protein -
Molecular Weight
- 35 kDa
Target
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