Complement C5b, 6 Complex (Active) Protein
This protein is expressed in .
Catalog No. ABIN935928
Quick Overview for Complement C5b, 6 Complex (Active) Protein (ABIN935928)
Target
Complement C5b, 6 Complex
Biological Activity
Active
Origin
Human
Host
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/ml
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Buffer
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Supplied as a frozen liquid with 10 mM HEPES and 120 mM NaCl, pH 7.2.
Biohazard Informations: This protein is purified from human plasma, therefore precautions appropriate for handling any blood-derived product must be use. -
Storage
- -80 °C
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- Complement C5b, 6 Complex
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Background
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Complement C5b, 6 complex, is a product of complement activation of C5 and an intermediate in the formation of the C5b-9 membrane attack complex (MAC) of complement. Each pathway of complement generates proteolytic enzyme complexes which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing the highly potent anaphylatoxin C5a (74 amino acids) and activating C5b.This is the only proteolytic step in the assembly of the C5b-9 complex.
Description: Normal human serum. Synonyms: Anaphylatoxin C5b protein, C5 protein, Complement C5 protein, Complement C5b protein, Complement C5 precursor protein, Complement component 5 protein, CPAMD4 protein, C5b6 protein.
Target
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