TNFRSF13C Protein
Quick Overview for TNFRSF13C Protein (ABIN987765)
Target
See all TNFRSF13C ProteinsBiological Activity
Origin
Source
Purity
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Sequence
- MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLP
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Characteristics
- Fully biologically active when compared to standard. Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 1.0-5.0 µg/ml in the presence of 1.0µg/ml of human soluble BAFF,corresponding to a specific activity of > 2.0×102 units/mg.
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Endotoxin Level
- Level Less than 1EU/µg of rHuBAFF-R as determined by LAL method
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Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His tag)
TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His-Avi Tag,Biotin)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (Fc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (mFc Tag)TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-175) protein (His tag)custom-made TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 1-184) protein (His tag)custom-made TNFRSF13C Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (Active) proteinTNFRSF13C Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 10-71) protein (Fc Tag)TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 7-71) protein (His tag)TNFRSF13C Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) (AA 10-71) (Active) protein (Fc Tag)TNFRSF13C Origin: Mouse Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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Storage
- 4 °C
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Alternative Name
- BAFF Receptor (BAFF-R)
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Background
- BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation. Synonym: BAFF Receptor ( BAFF-R), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 8.0, 500mM NaCl.
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Molecular Weight
- Approximately 7.7 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.
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Pathways
- NF-kappaB Signaling
Target
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