COL18A1 Protein
Quick Overview for COL18A1 Protein (ABIN987805)
Target
See all COL18A1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Characteristics
- Determined by Endothelial Cell Tube Formation. The cells treated with 10myg/ml Endostatin showed significant anti-angiogenesis effect.
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Endotoxin Level
- level is less than 0.1 ng per myg (1EU/myg) of Endostatin
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Collagen, Type XVIII, alpha 1 (COL18A1) protein (His tag)
COL18A1 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE
Collagen, Type XVIII, alpha 1 (COL18A1) protein (KLH)COL18A1 Origin: Human Host: Synthetic > 95 % WB, SDS, ELISA, IP
Collagen, Type XVIII, alpha 1 (COL18A1) (Transcript Variant 2) (Active) proteinCOL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (GST tag)COL18A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Collagen, Type XVIII, alpha 1 (COL18A1) (AA 1578-1754) protein (His tag)COL18A1 Origin: Human Host: Yeast Recombinant > 90 % SDS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- -20 °C
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- COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
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Alternative Name
- Endostatin
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Target Type
- Chemical
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Background
- Endostatin is a cleaved product of the carboxyl-terminal domain of collagen XVIII. It functions as an anti-angiogenic cytokine that is expressed in various organs especially with high levels in liver, lung, and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant Endostatin expressed in yeast, whichcauses G1 arrest of endothelial cells. Endostatin treatment results in apoptosis of HUVE and HMVE cells. Recombinant human Endostatin is a 20.2 kDa protein consisting of 184 amino acid residues. Synonym: Endostatin 3 3 . Formulation: The sterile filtered solution was lyophilized with 17 mM citric-phosphate buffer, pH 6.2. .
Target
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