IL1A Protein
-
- Target See all IL1A Proteins
- IL1A (Interleukin 1 alpha (IL1A))
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Sequence
- SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQ
- Characteristics
- Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant stimulation of mouse D10S cells is less than 0.001 ng/ml, corresponding to aof 1 x 109 IU/mg
- Purity
- > 97 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rHuIL-1alpha as determined by LAL method
- Top Product
- Discover our top product IL1A Protein
-
Interleukin 1 alpha (IL1A) (Active) protein
IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (Fc Tag)IL1A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant 97,00% SDS
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
- Storage
- 4 °C
-
- Target
- IL1A (Interleukin 1 alpha (IL1A))
- Alternative Name
- Interleukin-1 alpha (IL-1alpha) (IL1A Products)
- Background
- IL-1 alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Synonym: Interleukin-1 alpha ( IL-1alpha) , Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
- Molecular Weight
- Approximately 18.0 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.
- Pathways
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
-
