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IL-33 Protein

IL33 Origin: Mouse Host: Escherichia coli (E. coli) > 98 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN988078
  • Target See all IL-33 (IL33) Proteins
    IL-33 (IL33) (Interleukin 33 (IL33))
    Biological Activity
    Active
    Origin
    • 22
    • 18
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 28
    • 12
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequence
    SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSK
    Characteristics
    Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2.0 x 106units/mg.
    Purity
    > 98 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rMuIL-33 as determined by LAL method
    Top Product
    Discover our top product IL33 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at
    Storage
    4 °C
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Alternative Name
    Interleukin-33 (IL-33) (IL33 Products)
    Background
    IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Synonym: Interleukin-33 (IL-33), Mouse. Formulation: Lyophilized from a 0.2µm filtered solution in PBS, EDTA and DTT, pH 7.4.
    Molecular Weight
    Approximately 17.5 kDa protein containing 158 amino acid residues.
    Pathways
    Production of Molecular Mediator of Immune Response
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