Browse our Natural Cytotoxicity Triggering Receptor 3 Proteins (NCR3)

Full name:: Natural Cytotoxicity Triggering Receptor 3 Proteins (NCR3)

On www.antibodies-online.com are 32 Natural Cytotoxicity Triggering Receptor 3 (NCR3) Proteins from 11 different suppliers available. Additionally we are shipping Natural Cytotoxicity Triggering Receptor 3 Antibodies (124) and Natural Cytotoxicity Triggering Receptor 3 Kits (6) and many more products for this protein. A total of 169 Natural Cytotoxicity Triggering Receptor 3 products are currently listed.

Synonyms:: 1C7, CD337, LY117, MALS, MGC133750, Nkp30

list all proteins	Gene Name	GeneID	UniProt
	NCR3	259197	O14931
	NCR3	294251
	NCR3
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Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) interaction partners

Low NKp30 expression on NK cells is associated with Nasopharyngeal Carcinoma.
we propose NKp30 status as a simple and early prognostic biomarker that identifies intermediate-risk patients with poor prognosis who otherwise may not be identified with existing risk stratification systems.
Data indicate a sequence of events driven by tumour-derived prostaglandin D2 (PGD2 (show PTGDS Proteins)) associated with engagement of the natural cytotoxicity triggering receptor 3 (NKp30)-B7H6 (show NCR3LG1 Proteins) antigen (B7H6 (show NCR3LG1 Proteins)) pathway leading to significant group 2 innate lymphoid cells (ILC2s) activation and expansion.
NKp44 (show NCR2 Proteins) and NKp30 splice variants profiles are tissue/condition specific and demonstrate similarity between placenta and cancerous tissues.
Results found that rs2736191-C NCR3 carriers had a significant increased number of mild malaria episodes compared to the non-carriers. This SNP had a significantly increased promoter activity in NCR33 gene and involves a binding site for STAT4 (show STAT4 Proteins) and RUNX3 (show RUNX3 Proteins).
findings show HIV reservoir size is dependent on the presence of a defined NK cell population with a specific transcriptional signature: high NCR (NKp46 (show NCR1 Proteins) and NKp30) and IFN-gamma (show IFNG Proteins) inducibility upon NCR and cytokine receptor (show EBI3 Proteins) engagement
Copy number variations of HLA-I and activation of NKp30 pathway determine the sensitivity of gastric cancer cells to the cytotoxicity of natural killer cells
Data suggest that NK cells and NKp30 could play a role in Antisynthetase syndrome pathogenesis.
the stalk domains of NKp30 and NKp46 (show NCR1 Proteins), another NCR employing CD3zeta (show CD247 Proteins) for signaling, were not exchangeable without drastic deficiencies in folding, plasma membrane targeting, and/or ligand-induced receptor signaling.
Age and CMV serostatus influence the expression of NKp30, NKp46 (show NCR1 Proteins) and DNAM-1 (show CD226 Proteins) activating receptors on resting and IL-2 (show IL2 Proteins) activated natural killer cells.

Chimpanzee Natural Cytotoxicity Triggering Receptor 3 (NCR3) interaction partners

phenotypic, molecular, and functional characterization for triggering molecules (NKp46 (show NCR1 Proteins), NKp30 NKp80 (show KLRF1 Proteins), and NKG2D (show KLRK1 Proteins); in this AIDS-resistant species, relevant differences to human NK cells involve NKp80 (show KLRF1 Proteins) and particularly NKp30

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Protein Profile

Protein Summary

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Natural Cytotoxicity Triggering Receptor 3 (NCR3)

natural cytotoxicity triggering receptor 3 (NCR3)
natural cytotoxicity triggering receptor 3 (Ncr3)

1C7 protein
CD337 protein
LY117 protein
MALS protein
MGC133750 protein
Nkp30 protein

Protein level used designations for NCR3

natural cytotoxicity triggering receptor 3 , NK-p30 , activating NK-A1 receptor , activating natural killer receptor p30 , lymphocyte antigen 117 , natural killer cell p30-related protein , NK receptor 1c7 , natural killer cell p30-related

GENE ID	SPECIES
513769	Bos taurus
100270822	Sus scrofa
259197	Homo sapiens
294251	Rattus norvegicus
607220	Canis lupus familiaris
449613	Pan troglodytes
715574	Macaca mulatta

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