Browse our anti-MED23 (MED23) Antibodies

Full name:: anti-Mediator Complex Subunit 23 Antibodies (MED23)

On www.antibodies-online.com are 60 Mediator Complex Subunit 23 (MED23) Antibodies from 15 different suppliers available. Additionally we are shipping MED23 Kits (11) and MED23 Proteins (4) and many more products for this protein. A total of 81 MED23 products are currently listed.

Synonyms:: 130kDa, 3000002A17Rik, ARC130, CG3695, crsp3, CRSP130, CRSP133, Dmel\\CG3695, DRIP130, dSUR2, dTRAP150beta, ESTM7, Gal11/SUR2, MED23, mKIAA1216, MRT18, si:ch211-272f15.2, SUR-2, Sur2, Trap150, Trap150beta, X83317, zgc:91979

list all antibodies	Gene Name	GeneID	UniProt
	MED23	9439	Q9ULK4
	MED23	70208	Q80YQ2
	MED23	309565
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Most Popular Reactivities for anti-MED23 (MED23) Antibodies

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anti-Human MED23 Antibodies:

anti-Mouse (Murine) MED23 Antibodies:

anti-Rat (Rattus) MED23 Antibodies:

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Relevant Pathways for anti-MED23 Antibodies

Regulation of Lipid Metabolism by PPARalpha

More product categories related to MED23 Antibody

Top referenced anti-MED23 Antibodies

Human Polyclonal MED23 Primary Antibody for ChIP, IP - ABIN152372 : Meyer, Donner, Knuesel, York, Espinosa, Taatjes: Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. in The EMBO journal 2008 (PubMed)
Show all 5 Pubmed References
Human Polyclonal MED23 Primary Antibody for IP - ABIN152373 : Terada, Saitoh, Ohno, Komada, Saitoh, Peles, Ohno: Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves. in Molecular and cellular biology 2011 (PubMed)
Show all 4 Pubmed References
Human Polyclonal MED23 Primary Antibody for WB - ABIN152374 : Ablack, Cohen, Thillainadesan, Fonseca, Pelka, Torchia, Mymryk: Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. in Journal of virology 2012 (PubMed)

More Antibodies against MED23 Interaction Partners

Human Mediator Complex Subunit 23 (MED23) interaction partners

This is the first patient with documented refractory epilepsy caused by a novel homozygous pathogenic variant in MED23 expanding the phenotypic spectrum. Identification of the underlying genetic defect in MED23 sheds light on the possible mechanism of complete response to the ketogenic diet in this child.
a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (show MPO Antibodies), CEACAM8, CRISP3 (show CRISP3 Antibodies), MS4A3 (show MS4A3 Antibodies), CEACAM6, HEMGN (show HEMGN Antibodies), and MMP8 (show MMP8 Antibodies)
Higher l-arginine (show GATM Antibodies) was associated with higher risk of Ischemic heart disease (odds ratio and of myocardial infarction, based on 2 SNPs from MED23.
MED23-associated intellectual disability has been found in two brothers from a non-consanguineous family.
MED23 plays an important role in hepatocarcinogenesis, and it may be a novel target for HCC (show FAM126A Antibodies) therapy.
Upregulation of mediator MED23 in non-small-cell lung cancer promotes the growth, migration, and metastasis of cancer cells.
Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb (show CCNT1 Antibodies).
Data show that Med23 RNAi specifically inhibits the proliferation and tumorigenicity of lung cancer cells with hyperactive Ras activity.
missense mutation (p. R617Q) in MED23 that cosegregates with nonsyndromic autosomal recessive intellectual disability; mutation impaired response of JUN and FOS to mitogens by altering interaction between enhancer-bound transcription factors and Mediator
DRIP130 regulates HER2 (show ERBB2 Antibodies) expression by binding to ESX (show ELF3 Antibodies)

Mouse (Murine) Mediator Complex Subunit 23 (MED23) interaction partners

MED23 constitutes a molecular node in the regulatory network of anabolic bone formation and related diseases.
Med23 contributes to controlling T-cell activation at the transcriptional level and prevents the development of autoimmunity.
The hepatic Med23 deletion impaired the Mediator and RNAPII (show 0 Antibodies) recruitment and attenuated the expression of FOXO1 (show FOXO1 Antibodies) target genes.
Data show that Kruppel-like transcription factors KLF2 (show KLF2 Antibodies) expression is decreased in mediator complex Med23 null thymocytes.
Mediator Med23 deficiency enhances neural differentiation of murine embryonic stem cells through modulating BMP signaling.
Reduced expression of MED23 inhibits cell apoptosis by downregulation of Bax (show BAX Antibodies), activated Caspase 3 (show CASP3 Antibodies), activated Caspase 9 (show CASP9 Antibodies) and upregulation of cyclinD1 and Bcl2 (show BCL2 Antibodies).
Data show tha tMed23 deficiency in fibroblasts selectively inhibited the oncogenic transformation induced by Ras.
Mediator MED23 controls the cell fate preference that directs differentiation into smooth muscle cells (SMCs) or adipocytes
MED23 regulates a subset of hnRNP L (show HNRNPL Antibodies)-targeted alternative splicing (AS) and alternative cleavage and polyadenylation (APA (show ENPEP Antibodies)) events.
MED23 Mediator controls Egr1 (show EGR1 Antibodies) gene and stimulates Pol II (show 0 Antibodies) initiation at a step subsequent to preinitiation complex assembly

Caenorhabditis elegans (C. elegans) Mediator Complex Subunit 23 (MED23) interaction partners

we investigate orthologs of a transcription complex that acts in mammalian EGFR (show EGFR Antibodies) signaling-lin-1/Elk1 (show ELK1 Antibodies), sur-2/Med23, and the Cdk8 (show CDK8 Antibodies) Kinase module (CKM (show CKM Antibodies)).our analysis using cell fate reporters reveals that both EGFR (show EGFR Antibodies) and LIN-12/Notch (show NOTCH1 Antibodies) signal transduction pathways are active in all VPCs in lin-1/Elk1 (show ELK1 Antibodies) mutants
Study shows that sur-2 mutation affects the Cbr (show CNR1 Antibodies)-sur-2/MED23 gene that is orthologous to a C. elegans gene critical for the normal response to the EGF (show EGF Antibodies) signal. whereas Cel-sur-2 mutants exhibit a reduced vulval development because of defects in the VPC immediately adjacent to the anchor cell (the P6.p cell), similar defects in Caenorhabditis briggsae -sur-2 mutants do not have the same impact.

MED23 Antigen Profile

Antigen Summary

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with MED23

Mediator complex subunit 23 (MED23) antibody
mediator complex subunit 23 (MED23) antibody
mediator complex subunit 23 (med23) antibody
mediator of RNA polymerase II transcription subunit 23 (LOC412332) antibody
mediator complex subunit 23 (Med23) antibody
mediator complex subunit 23 L homeolog (med23.L) antibody
Mediator of RNA polymerase II transcription subunit 23 (sur-2) antibody

130kDa antibody
3000002A17Rik antibody
ARC130 antibody
CG3695 antibody
crsp3 antibody
CRSP130 antibody
CRSP133 antibody
Dmel\\CG3695 antibody
DRIP130 antibody
dSUR2 antibody
dTRAP150beta antibody
ESTM7 antibody
Gal11/SUR2 antibody
MED23 antibody
mKIAA1216 antibody
MRT18 antibody
si:ch211-272f15.2 antibody
SUR-2 antibody
Sur2 antibody
Trap150 antibody
Trap150beta antibody
X83317 antibody
zgc:91979 antibody

Protein level used designations for MED23

, , , , , , , , , , , , , , , , , , , CG3695-PA CG3695-PB MED23-PA MED23-PB mediator complex subunit 23 mediator complex subunit n23 cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa Sp1 transcriptional activation cofactor subunit 3 mediator of RNA polymerase II transcription subunit 23-like mediator of RNA polymerase II transcription subunit 23 130 kDa transcriptional co-activator 133 kDa transcriptional co-activator activator-recruited cofactor 130 kDa component cofactor required for Sp1 transcriptional activation subunit 3 vitamin D3 receptor interacting protein CRSP complex subunit 3 cofactor required for Sp1 transcriptional activation, subunit 3 (130kD) mSur-2 protein sur-2 homolog cofactor required for Sp1 transcriptional activation, subunit 3

GENE ID	SPECIES
37639	Drosophila melanogaster
426927	Gallus gallus
472124	Pan troglodytes
474822	Canis lupus familiaris
100067556	Equus caballus
100342894	Oryctolagus cuniculus
100409950	Callithrix jacchus
100433008	Pongo abelii
100545205	Meleagris gallopavo
100562268	Anolis carolinensis
100602785	Nomascus leucogenys
412332	Apis mellifera
100466100	Ailuropoda melanoleuca
9439	Homo sapiens
70208	Mus musculus
309565	Rattus norvegicus
445483	Danio rerio
399060	Xenopus laevis
513610	Bos taurus
173345	Caenorhabditis elegans

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Show all anti-Mediator Complex Subunit 23 (MED23) Antibodies with Pubmed References