Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MED12 Antibodies

(Mediator Complex Subunit 12 (MED12))
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009].
MED12 antibody  (AA 1742-2011) MED12 antibody  (AA 1742-2011) MED12 antibody (AA 1742-2011) (ABIN7159104)

MED12 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

MED12 antibody  (AA 1829-1941) MED12 antibody  (AA 1829-1941) MED12 antibody (AA 1829-1941) (ABIN564287)

MED12 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated

MED12 antibody  (Center) MED12 antibody  (Center) MED12 antibody (Center) (ABIN2707199)

MED12 Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated

MED12 Antibodies by Grade

Find MED12 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MED12 Antibodies by Reactivity

Find MED12 Antibodies for a variety of species such as anti-Human MED12, anti-Mouse MED12, anti-Rat MED12. The species listed below are among those available. Click on a link to go to the corresponding products.

MED12 Antibodies by Application

Find MED12 Antibodies validated for a specific application such as ELISA, WB, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

MED12 Antibodies by Host

Find MED12 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MED12 Antibodies by Binding Specificity

Find MED12 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MED12 Antibodies by Clonality

Find available monoclonal or polyclonal MED12 Antibodies. Click on a link to go to the corresponding products.

MED12 Antibodies by Clone

Find MED12 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MED12 Antibodies by Conjugate

Find MED12 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MED12 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN1534053
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
Cat. No. ABIN5675220
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
Cat. No. ABIN7188318
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p)
Validations
Cat. No. ABIN6287309
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN1590067
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7159105
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7159106
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7159107
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
Cat. No. ABIN7243679
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
Cat. No. ABIN7134788
Quantity 150 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC, WB
Validations
Cat. No. ABIN7093914
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p), WB
Validations
Cat. No. ABIN6242936
Quantity 400 μL
Datasheet Datasheet
Reactivity Chicken
Application IHC, WB
Validations
Cat. No. ABIN195709
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (fro), IHC (p), WB
Validations
Cat. No. ABIN5675221
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN6976774
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MED12 Antibodies

Cao, Jiang, Wang, Zhang, Al-Hendy, Mamillapalli, Kallen, Kodaman, Taylor, Li, Huang: "H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas." in: Oncogene, Vol. 38, Issue 27, pp. 5356-5366, (2019) (PubMed).

Shen, Szewczyk, Eram, Smil, Kaniskan, de Freitas, Senisterra, Li, Schapira, Brown, Arrowsmith, Barsyte-Lovejoy, Liu, Vedadi, Jin: "Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6." in: Journal of medicinal chemistry, Vol. 59, Issue 19, pp. 9124-9139, (2016) (PubMed).

Vogl, Reiprich, Küspert, Kosian, Schrewe, Nave, Wegner: "Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 15, pp. 6679-90, (2013) (PubMed).

Wagner, DeLuca: "Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription." in: PLoS ONE, Vol. 8, Issue 10, pp. e78242, (2013) (PubMed).

Rienzo, Casamassimi, Schiano, Grimaldi, Infante, Napoli: "Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation." in: Biochimie, Vol. 94, Issue 8, pp. 1828-32, (2012) (PubMed).

Miyanari, Torres-Padilla: "Control of ground-state pluripotency by allelic regulation of Nanog." in: Nature, Vol. 483, Issue 7390, pp. 470-3, (2012) (PubMed).

Pérot, Croce, Ribeiro, Lagarde, Velasco, Neuville, Coindre, Stoeckle, Floquet, MacGrogan, Chibon: "MED12 alterations in both human benign and malignant uterine soft tissue tumors." in: PLoS ONE, Vol. 7, Issue 6, pp. e40015, (2012) (PubMed).

Valdez, Nieto, Murray, Li, Wang, Champlin, Andersson: "Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines." in: Experimental hematology, Vol. 40, Issue 10, pp. 800-10, (2012) (PubMed).

Langlais, Couture, Sylvain-Drolet, Drouin: "A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 2, pp. 348-59, (2011) (PubMed).

DAlessio, Ng, Willenbring, Tjian: "Core promoter recognition complex changes accompany liver development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 10, pp. 3906-11, (2011) (PubMed).

Aliases for MED12 Antibodies

mediator complex subunit 12 (MED12) Antibodies
mediator complex subunit 12 (Med12) Antibodies
mediator complex subunit 12 (med12) Antibodies
230kDa Antibodies
ARC240 Antibodies
CAGH45 Antibodies
FGS1 Antibodies
HOPA Antibodies
MED12S Antibodies
Mopa Antibodies
OHDOX Antibodies
OKS Antibodies
OPA-1 Antibodies
OPA1 Antibodies
TNRC11 Antibodies
Tnrc11 Antibodies
TRAP230 Antibodies
Trap230 Antibodies
You are here:
Support