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MECP2 Antibodies

(Methyl CpG Binding Protein 2 (MECP2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].
MECP2 antibody  (AA 7-148) MECP2 antibody  (AA 7-148) MECP2 antibody (AA 7-148) (ABIN5542475)

MECP2 Reactivity: Human ELISA, FACS, ICC, IHC, WB Host: Mouse Monoclonal 8H4A5B9 unconjugated

MECP2 antibody  (AA 1-486) MECP2 antibody  (AA 1-486) MECP2 antibody (AA 1-486) (ABIN517815)

MECP2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

MECP2 antibody MECP2 antibody MECP2 antibody (ABIN7130211)

MECP2 Reactivity: Human ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

MECP2 Antibodies by Reactivity

Find MECP2 Antibodies for a variety of species such as anti-Human MECP2, anti-Mouse MECP2, anti-Rat MECP2. The species listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Antibodies by Application

Find MECP2 Antibodies validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MECP2 Antibodies by Host

Find MECP2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Antibodies by Binding Specificity

Find MECP2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Antibodies by Clonality

Find available monoclonal or polyclonal MECP2 Antibodies. Click on a link to go to the corresponding products.

MECP2 Antibodies by Clone

Find MECP2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

MECP2 Antibodies by Conjugate

Find MECP2 Antibodies with a specific conjugate such as Biotin, HRP, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MECP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (3)
Cat. No. ABIN6263186
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ChIP, ELISA, WB
Validations
  • (3)
Cat. No. ABIN6655271
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN2966798
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application EIA, FACS, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN953366
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Mouse
Application ChIP, ELISA, WB
Validations
  • (3)
Cat. No. ABIN537792
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN6254071
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1869144
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2781332
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae
Application WB
Validations
  • (2)
Cat. No. ABIN2777533
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2780632
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN6255514
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, WB
Validations
  • (2)
Cat. No. ABIN6263185
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IHC, ELISA, WB
Validations
  • (2)
Cat. No. ABIN3031763
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7159621
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (1)
Cat. No. ABIN6254070
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MECP2 Antibodies

Zhou, Guo, Huang, Yu, Xu, Long: "Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2." in: Molecular oncology, Vol. 14, Issue 9, pp. 2231-2250, (2021) (PubMed).

Buck, ONeill, Stitzel et al.: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." in: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).

Liu, Ni, Sun: "Expression of Phospho-MeCP2s in the Developing Rat Brain and Function of Postnatal MeCP2 in Cerebellar Neural Cell Development." in: Neuroscience bulletin, Vol. 33, Issue 1, pp. 1-16, (2017) (PubMed).

Liu, Lai, Ma, Ke, Zhang, Liu, Zhang, Pei, Li, Yi, Shu, Shang, Liang, Huang: "CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression." in: Nature communications, Vol. 8, Issue 1, pp. 355, (2017) (PubMed).

Maphis, Jiang, Binder, Wright, Gopalan, Lamb, Bhaskar: "Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology." in: Frontiers in molecular neuroscience, Vol. 10, pp. 69, (2017) (PubMed).

Tai, Liu, Hsu, Ma, Cheng, Liu, Lee: "MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome." in: Nature communications, Vol. 7, pp. 10552, (2016) (PubMed).

Ma, Li, Li, Yang, Huang, Meng, Zhang, Li: "Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells." in: International immunopharmacology, (2015) (PubMed).

Ganguly, Chen, Shin, Devaskar: "Prenatal caloric restriction enhances DNA methylation and MeCP2 recruitment with reduced murine placental glucose transporter isoform 3 expression." in: The Journal of nutritional biochemistry, Vol. 25, Issue 2, pp. 259-66, (2014) (PubMed).

Lu, Yang, Chen, Su, Huang, Tsai, Wang, Tseng, Hwang: "Modeling neurogenesis impairment in Down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells." in: Experimental cell research, Vol. 319, Issue 4, pp. 498-505, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Aliases for MECP2 Antibodies

methyl-CpG binding protein 2 (MECP2) Antibodies
methyl CpG binding protein 2 (Mecp2) Antibodies
methyl CpG binding protein 2 (mecp2) Antibodies
methyl-CpG binding protein 2 S homeolog (mecp2.S) Antibodies
1500041B07Rik Antibodies
AUTSX3 Antibodies
BB130002 Antibodies
D630021H01Rik Antibodies
Mbd5 Antibodies
MRX16 Antibodies
MRX79 Antibodies
MRXS13 Antibodies
MRXSL Antibodies
PPMX Antibodies
RS Antibodies
RTS Antibodies
RTT Antibodies
WBP10 Antibodies
wu:fk96a04 Antibodies
zgc:111857 Antibodies
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