TEAD2 Proteins
4 TEA Domain Family Member 2 (TEAD2) Proteins from 2 manufacturers are available on www.antibodies-online.com.
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TEA Domain Family Member 2 (TEAD2) (AA 1-447) protein (His tag) Protein
TEA Domain Family Member 2 (TEAD2) (AA 1-445) protein (His tag) Protein
TEA Domain Family Member 2 (TEAD2) (AA 1-447) protein (GST tag) Protein
TEA Domain Family Member 2 (TEAD2) (AA 218-307) protein (GST tag) Protein
TEAD2 Protein Profile
Protein Summary
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction (By similarity). Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
Alternative names and synonyms associated with TEAD2
- TEA domain transcription factor 2 (TEAD2) antibody
- TEA domain family member 2 (Tead2) antibody
- TEA domain transcription factor 2 (Tead2) antibody
- Etdf antibody
- ETF antibody
- TEAD-2 antibody
- TEAD2 antibody
- TEF-4 antibody
- TEF4 antibody
Protein level used designations for TEAD2
TEA domain family member 2 , transcriptional enhancer factor TEF-4-like , transcriptional enhancer factor TEF-4 , ETEF-1 , embryonic TEA domain-containing factor , Embryonic TEA domain containing factor
GENE ID | SPECIES |
---|---|
456201 | Pan troglodytes |
484381 | Canis lupus familiaris |
100051732 | Equus caballus |
100461589 | Pongo abelii |
100597345 | Nomascus leucogenys |
8463 | Homo sapiens |
21677 | Mus musculus |
100125315 | Bos taurus |
308582 | Rattus norvegicus |
100625350 | Sus scrofa |
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