Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Rat (Rattus) Antibodies:
anti-Mouse (Murine) Antibodies:
Go to our pre-filtered search.
Human Polyclonal ALDH1A2 Primary Antibody for IHC, IHC (p) - ABIN4279209
Kostareli, Holzinger, Bogatyrova, Hielscher, Wichmann, Keck, Lahrmann, Grabe, Flechtenmacher, Schmidt, Seiwert, Dyckhoff, Dietz, Höfler, Pawlita, Benner, Bosch, Plinkert, Plass, Weichenhan, Hess: HPV-related methylation signature predicts survival in oropharyngeal squamous cell carcinomas. in The Journal of clinical investigation 2013
Show all 4 Pubmed References
The authors findings indicate that the SNP rs4238326 in ALDH1A2 gene may potentially modify individual susceptibility to knee OA in the Chinese population.
high transcription activities of ALDH1A2, ALDH1A3 (show ALDH1A3 Antibodies) and ALDH1L1 (show ALDH1L1 Antibodies) predicted worsen overall survival in gastric cancer patients
Data show that hRALDH2 is not inhibited by its oxidation product, all-trans-RA, suggesting the absence of a negative feedback regulatory loop. Expression of the Raldh2 gene is known to be regulated by RA itself, suggesting that the main regulation of the hRALDH2 activity level is transcriptional.
Study shows no evidence that genetic variants alter prostate cancer incidence, but show that SNPs in the ALDH1A2 gene affect prostate cancer mortality.
a critical role of ALDH1A2-RAR (show RARA Antibodies) signaling in the pathogenesis of head and neck cancer.
High expression of ALDH1A2 and ALDH1B1 (show ALDH1B1 Antibodies) mRNA was found to be significantly correlated to worser survival in all NSCLC patients.
the distribution of RALDH1 (show ALDH1A1 Antibodies), RALDH2, and RALDH3 (show ALDH1A3 Antibodies) in the postnatal eye was determined.
ALDH1A2 is involved in the regulation of cancer stem cell properties in neuroblastoma (show ARHGEF16 Antibodies).
Genetic association replicative and exploratory studies identify SNPs in ADA (show ADA Antibodies) and MTR (show MTR Antibodies) highly associated with isolated Neural tube defects (NTD)and SNP in ARID1A (show ARID1A Antibodies) and ALDH1A2 associated with NTDs in whites and African Americans respectively.
At the transcript level, the cisplatin + DEAB-resistant cells showed upregulated mRNA expression levels for ALDH1A2, ALDH1A3 (show ALDH1A3 Antibodies) isozymes and CD44 (show CD44 Antibodies) indicating the involvement of these markers in conferring chemoresistance
Zebrafish foxc1a plays a crucial role in early somitogenesis by restricting the expression of Raldh2 directly.
The novel aldh1a2 reporter line is driven by the complete set of regulatory sequences required for zebrafish development, reports novel sources of RA synthesis, and identifies the source of RA that promotes vertebral ossification.
aldh1a2 participate to a positive loop required for branchial arches development in zebrafish
Aldh1a2 is the primary aldehyde dehydrogenase acting during pancreas development and maternal Aldh1a2 activity persists in aldh1a2(um22) and aldh1a2(i26) mutant embryos.
Studies indicate that raldh2 expression is critical for the formation of wound epithelium and blastema.
data do not support the hypothesis that retinal itself represses weight gain and adipogenesis independently of RA. Instead, the data indicate that Raldh1 (show ALDH1A1 Antibodies) functions as a retinal and atRA-independent promoter of adiposity during adolescence, and enhances adiposity through pre-adipocyte cell autonomous actions
these studies identify Notch (show NOTCH1 Antibodies) signaling in dendritic cells as a crucial balancer of Th17/iTreg, which depends on the direct regulation of Aldh1a2 (show ALDH1A1 Antibodies) transcription in dendritic cells
ALDH2 (show ALDH2 Antibodies) mutation displays an inverse correlation of coronary collateral vessel formation in patients.
Data suggest that retinoic acid and GM-CSF (show CSF2 Antibodies)-induced retinal dehydrogenase 2 (RALDH2) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (show SP1 Antibodies) via the RA receptor/retinoid X receptor (show RXRB Antibodies) complex to the Aldh1a2 (show ALDH1A1 Antibodies) promoter.
all three proteins (RDH10 (show RDH10 Antibodies), RALDH2, and CRABP2 (show CRABP2 Antibodies)) appeared to be required for ATRA production induced by activation of PPARgamma (show PPARG Antibodies)
Defects in interdigital programmed cell death and digit separation in Hoxa13 (show HOXA13 Antibodies) mutant mice may be caused in part by reduced levels of RA signaling stemming from a loss in the direct regulation of Aldh1a2 (show ALDH1A1 Antibodies)
Raldh1 (show ALDH1A1 Antibodies) and Raldh3 (show ALDH1A3 Antibodies) influence enteric nervous system structure and function and heterozygosity for Raldh2 causes ENS defects
ALDH1A2 expression was highest in ALDH(very-br) cells, intermediate in ALDH(dim) cells, and lowest in ALDH(br) cells.
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.
rendered Fgfr2IIIb (show FGFR2 Antibodies)(-/-) embryos haploinsufficient for the Raldh2 and examined these embryos for the incidence and severity of duodenal atresia
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
, aldehyde dehydrogenase 1A2
, aldehyde dehydrogenase family 1 member A2
, aldehyde dehydrogenase family 1, subfamily A2
, retinal dehydrogenase 2
, retinal dehydrogenase, type II
, retinaldehyde-specific dehydrogenase type 2
, retinaldehyde dehydrogenase 2
, alcohol dehydrogenase family 1, subfamily A2
, alcohol dehydrogenase family 1, subfamily A7