ALDH1A2 antibody (N-Term)

Catalog No. ABIN2788209

This Rabbit Polyclonal antibody specifically detects ALDH1A2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for ALDH1A2 antibody (N-Term) (ABIN2788209)

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALDH1A2 Antibody

Binding Specificity: N-Term

Purpose: ALDH1A2 Antibody - N-terminal region

Sequence: PVYNPATGEQ VCEVQEADKA DIDKAVQAAR LAFSLGSVWR RMDASERGRL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ALDH1A2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH1A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59784-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2

Background:

Background Information: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Three transcript variants encoding distinct isoforms have been identified for this gene.

Gene Name: Aldehyde dehydrogenase 1 family, member A2

Alternative Symbols: RALDH2, RALDH2-T, RALDH(II)

Protein Name: Retinal dehydrogenase 2

Molecular Weight: 57kDa

Gene ID: 8854

NCBI Accession: NP_003879

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway