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anti-Human CTBP1 Antibodies:
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Human Polyclonal CTBP1 Primary Antibody for IF, IP - ABIN2473118
Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006
Human Polyclonal CTBP1 Primary Antibody for ICC, IP - ABIN192430
Valenta, Lukas, Korinek: HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. in Nucleic acids research 2003
Show all 2 Pubmed References
Human Polyclonal CTBP1 Primary Antibody for ICC, IF - ABIN4300741
Huang, Kesselman, Kizub, Guerrero-Preston, Ratovitski: Phospho-?Np63?/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure. in Cell cycle (Georgetown, Tex.) 2013
Dog (Canine) Polyclonal CTBP1 Primary Antibody for IHC, WB - ABIN2779661
Lin, Liang, Sun, Liang, Shi, Brunicardi, Shi, Feng: Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. in Molecular and cellular biology 2003
Show all 2 Pubmed References
through targeting CtBP1-mediated suppression of the Epithelial-mesenchymal transition process, miR (show MLXIP Antibodies)-644a might suppress the tumor metastasis of gastric cancer cells
Overall, our findings reveal that CtBP1/2 is essential to promote to human glioma cell growth through maintaining the DNA stability regulated by the MRN/ATR (show ANTXR1 Antibodies)/Chk1 (show CHEK1 Antibodies)/CDK2 (show CDK2 Antibodies)/HIF-1alpha (show HIF1A Antibodies) signaling pathway.
A review of CtBP (show CTBP2 Antibodies) structure, role in tumor progression, and discovery and development of CtBP (show CTBP2 Antibodies) inhibitors that target CtBP's dehydrogenase activity and other functions, with a focus on the theory and rationale behind the designs of current inhibitors. [review]
miR (show MLXIP Antibodies)-644a/CTBP1/p53 (show TP53 Antibodies) have roles in suppressing breast cancer drug resistance by inhibiting cell survival and epithelial-mesenchymal transition
Study reports a recurrent de novo C-terminal binding protein 1 (CTBP1) mutation is associated with developmental delay, hypotonia, ataxia, and tooth enamel defects. This is the first report of mutations within CTBP1 in association with any human disease.
Pinin (show PNN Antibodies) and CtBP1 and CtBP2 (show CTBP2 Antibodies) are oncotargets that closely interact with each other to regulate transcription and pre-mRNA alternative splicing and promote cell adhesion and other epithelial characteristics of ovarian cancer cells.
the importance of the oligomeric state of CtBP for coactivation of NeuroD1-dependent transcription, was investigated.
C-terminal binding protein 1 is a critical factor linking changes in cell metabolism to cell phenotype in hypoxic and other forms of pulmonary hypertension
CtBP1 increased breast tumor growth in MeS (show ME1 Antibodies) mice modulating multiple genes and miRNA expression implicated in cell proliferation, progenitor cells phenotype, epithelial to mesenchymal transition, mammary development and cell communication in the xenografts.
These data uncovered that CtBP1 protein is a valuable marker of glioma pathogenic process and that CtBP1 can serve as a novel prognostic marker for glioma therapy.
CtBP1 protein is not essential for the formation of functional ribbon synapses in the retina.
Study demonstrates differential regional and subcellular expression patterns for CtBP1 and CtBP2 (show CTBP2 Antibodies) in brain and reveals a previously unknown synaptic localization for CtBP2 (show CTBP2 Antibodies) in particular brain regions.
CtBp (show CTBP2 Antibodies) proteins repress transcription in a histone deacetylase (show HDAC1 Antibodies) dependent or independent manner.
The leukemia-associated transcription repressor AML1 (show RUNX1 Antibodies)/MDS1/EVI1 (show MECOM Antibodies) requires CtBP (show CTBP2 Antibodies) to induce abnormal growth and differentiation of murine hematopoietic cells.
Mice harboring various combinations of Ctbp1 and Ctbp2 (show CTBP2 Antibodies) mutant alleles exhibit dosage-sensitive defects in a wide range of developmental processes
Smad6 (show SMAD6 Antibodies) repressed bone morphogenetic protein-induced Id1 (show ID1 Antibodies) transcription through recruiting transcriptional corepressor C-terminal binding protein (CtBP (show CTBP2 Antibodies)).
Mono-ADP-ribosylation of CtBP1/BARS inactivates its repressor function, which leads to the activation of genes that regulate neutral lipid storage.
p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein.
basic Kruppel-like factor (show KLF3 Antibodies) gene (Klf3 (show KLF3 Antibodies)) has a role with CtBP (show CTBP2 Antibodies) in adipogenesis
In zebrafish hair cells exogenous Ribeye (show CTBP2 Antibodies) B-domain and CtBP1 localize to the basal ends of synaptic ribbons.
Tel (show ETV6 Antibodies) orchestrates endothelial sprouting by binding to the generic co-repressor, CtBP (show CTBP2 Antibodies)
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
C-terminal-binding protein 1
, brefeldin A-ribosylated substrate
, 50 kDa BFA-dependent ADP-ribosylation substrate
, 50-kDa BFA-induced ADP-ribosylated substrate
, C-terminal-binding protein 3
, C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate
, brefeldin A-ADP-riboslyated substrate
, C-terminal-binding protein A
, C-terminal binding protein 1
, C-terminal-binding protein 1-like
, c-terminal-binding protein 1-like
, LOW QUALITY PROTEIN: C-terminal-binding protein 1