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anti-Human CTBP1 Antibodies:
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Chicken Monoclonal CTBP1 Primary Antibody for IF, WB - ABIN968722
Furusawa, Moribe, Kondoh, Higashi: Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1. in Molecular and cellular biology 2000
Show all 4 Pubmed References
Human Polyclonal CTBP1 Primary Antibody for ICC, IP - ABIN192430
Valenta, Lukas, Doubravska, Fafilek, Korinek: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. in The EMBO journal 2006
Show all 2 Pubmed References
Human Polyclonal CTBP1 Primary Antibody for ICC, IF - ABIN4300741
Huang, Kesselman, Kizub, Guerrero-Preston, Ratovitski: Phospho-?Np63?/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure. in Cell cycle (Georgetown, Tex.) 2013
Dog (Canine) Polyclonal CTBP1 Primary Antibody for IHC, WB - ABIN2779661
Lin, Liang, Sun, Liang, Shi, Brunicardi, Shi, Feng: Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. in Molecular and cellular biology 2003
Show all 2 Pubmed References
In zebrafish hair cells exogenous Ribeye (show CTBP2 Antibodies) B-domain and CtBP1 localize to the basal ends of synaptic ribbons.
Tel (show ETV6 Antibodies) orchestrates endothelial sprouting by binding to the generic co-repressor, CtBP (show CTBP2 Antibodies)
miR (show MLXIP Antibodies)-644a/CTBP1/p53 (show TP53 Antibodies) have roles in suppressing breast cancer drug resistance by inhibiting cell survival and epithelial-mesenchymal transition
Study reports a recurrent de novo C-terminal binding protein 1 (CTBP1) mutation is associated with developmental delay, hypotonia, ataxia, and tooth enamel defects. This is the first report of mutations within CTBP1 in association with any human disease.
Pinin (show PNN Antibodies) and CtBP1 and CtBP2 (show CTBP2 Antibodies) are oncotargets that closely interact with each other to regulate transcription and pre-mRNA alternative splicing and promote cell adhesion and other epithelial characteristics of ovarian cancer cells.
the importance of the oligomeric state of CtBP for coactivation of NeuroD1-dependent transcription, was investigated.
C-terminal binding protein 1 is a critical factor linking changes in cell metabolism to cell phenotype in hypoxic and other forms of pulmonary hypertension
CtBP1 increased breast tumor growth in MeS (show ME1 Antibodies) mice modulating multiple genes and miRNA expression implicated in cell proliferation, progenitor cells phenotype, epithelial to mesenchymal transition, mammary development and cell communication in the xenografts.
These data uncovered that CtBP1 protein is a valuable marker of glioma pathogenic process and that CtBP1 can serve as a novel prognostic marker for glioma therapy.
human chorionic gonadotropin stimulated miR (show MLXIP Antibodies)-212, which down-regulated OLFM1 (show OLFM1 Antibodies) and CTBP1 expression in fallopian and endometrial epithelial cells to favor spheroid attachment
It is a putative target gene of miR (show MLXIP Antibodies)-137 in breast neoplasms.
CtBP physically interacted with TCF-4, and this interaction was significantly inhibited in the presence of MTOB. The above findings point to a novel role of CtBPs in the promotion of CSC growth and self-renewal
Study determined that PCBP2 (show PCBP2 Antibodies) specifically associates with components of this kinase cascade and regulates the activities of its downstream transcriptional coactivators.
data suggest that PCBP2 (show PCBP2 Antibodies) regulates p73 (show ARHGAP24 Antibodies) expression via mRNA stability and p73 (show ARHGAP24 Antibodies)-dependent biological function in ROS (show ROS1 Antibodies) production and cellular senescence.
PCBP2 (show PCBP2 Antibodies) overexpression rescues the Meis1 (show MEIS1 Antibodies) effects of Akt (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) pathway and hypertrophy of cardiomyocytes.
These data reveal that Pcbp1 (show PCBP1 Antibodies) and Pcbp2 (show PCBP2 Antibodies) are individually essential for mouse embryonic development and have distinct impacts on embryonic viability and that Pcpb2 has a nonredundant in vivo role in hematopoiesis.
PCBP2 (show PCBP2 Antibodies) knockdown promoted angiotensin II-induced hypertrophy (increase in cell size, protein synthesis and activation of fetal genes) of cardiomyocytes, while PCBP2 (show PCBP2 Antibodies) overexpression obtained oppose effects.
Our analysis of PCBP1 (show PCBP1 Antibodies) and PCBP2 (show PCBP2 Antibodies) expression demonstrates robust expression of these two proteins within the gastric epithelium with high concordance for both proteins in their cell-type specificities and intracellular distributions.
This study demonstrates for the first time that alpha-CP2 (show PCBP2 Antibodies) functions as a transcriptional activator by binding to a single-stranded poly(C) sequence.
This study provides evidence that PCBP2 (show PCBP2 Antibodies) and hnRNP A1 (show HNRNPA1 Antibodies) bind to the 5' and 3' ends of the murine norovirus 1 viral RNA and contribute to RNA circularization, playing a role in the virus life cycle.
CtBP1 protein is not essential for the formation of functional ribbon synapses in the retina.
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
C-terminal binding protein 1
, C-terminal-binding protein 1
, C-terminal-binding protein 1-like
, c-terminal-binding protein 1-like
, brefeldin A-ribosylated substrate
, C-terminal-binding protein A
, 50 kDa BFA-dependent ADP-ribosylation substrate
, 50-kDa BFA-induced ADP-ribosylated substrate
, C-terminal-binding protein 3
, C-terminus binding protein 3/brefeldin A (BFA) adenosine diphosphate-ribosylated substrate
, brefeldin A-ADP-riboslyated substrate
, heterogeneous nuclear ribonucleoprotein X
, hnRNP X
, poly(rC)-binding protein 2
, putative heterogeneous nuclear ribonucleoprotein X