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Human Polyclonal SP100 Primary Antibody for IHC (p), WB - ABIN948494
Adler, Tavalai, Müller, Stamminger: Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100. in The Journal of general virology 2011
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Human Polyclonal SP100 Primary Antibody for IHC (p), WB - ABIN520413
Full, Jungnickl, Reuter, Bogner, Brulois, Scholz, Stürzl, Myoung, Jung, Stamminger, Ensser: Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity. in PLoS pathogens 2014
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Human Polyclonal SP100 Primary Antibody for CM, IHC - ABIN4355450
Stepp, Meyers, McBride: Sp100 provides intrinsic immunity against human papillomavirus infection. in mBio 2013
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Human Monoclonal SP100 Primary Antibody for RNAi, ELISA - ABIN562971
Berard, Coombs, Severini: Quantification of the host response proteome after herpes simplex virus type 1 infection. in Journal of proteome research 2015
identification and analysis of the genes Sp100, Csprs, and Ifi75 (show SP110 Antibodies) in two members of the genus Mus (show TRPV6 Antibodies), M. musculus and M. caroli
the ND10 bodies become viral replication compartments, and ICP0, a viral E3 ligase, degrades both PML (show PML Antibodies) and SP100. The amounts of PML (show PML Antibodies) and SP100 and the number of ND10 structures increase in cells exposed to IFN-beta (show IFNB1 Antibodies).
that Sp100 represses viral transcription and replication in differentiated cells
Data suggest that nuclear antigen Sp100C is a multifaceted histone H3 (show HIST3H3 Antibodies) methylation and phosphorylation sensor.
These results suggest that high-risk human papillomavirus 31 target interferon kappa to prevent Sp100 expression and identify Sp100 as an interferon (show IFNA Antibodies)-stimulated gene with anti-human papillomavirus activity.
PML (show PML Antibodies), hDaxx (show DAXX Antibodies) and Sp100 primarily act as cellular restriction factors during lytic human cytomegalovirus replication and during the dynamic process of reactivation but do not serve as key determinants for the establishment of latency.
Sp100 repressed viral transcription and replication only during the initial stages of viral establishment, suggesting that Sp100 acts as a repressor of incoming human papillomavirus type 18 DNA.
Sp100 depletion promotes Adenovirus progeny production and early viral protein synthesis.
Two regions within the N-terminal of the herpes simplex virus 1 ICP0 facilitate the degradation and dissociation of host PML (show PML Antibodies) and dissociation of Sp100 from ND10.
Sp100 is recruited to activated arrays in cells expressing the herpes simplex virus type 1 E3 ubiquitin ligase (show MUL1 Antibodies), ICP0, which degrades all Sp100 isoforms except unsumoylated Sp100A.
The results suggest that hantavirus infection interferes with DAXX (show DAXX Antibodies)-mediated apoptosis, and expression of interferon-activated (show MNDA Antibodies) Sp100 and ISG-20 (show ISG20 Antibodies) proteins may indicate intracellular intrinsic antiviral attempts.
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene\; one of which encodes a high-mobility group protein.
SP100 nuclear antigen
, nuclear autoantigen Sp-100
, nuclear autoantigen Sp-100-like
, nuclear dot-associated Sp100 protein
, speckled 100 kDa
, SP100-HMG nuclear autoantigen
, nuclear antigen Sp100
, Nuclear autoantigen Sp-100
, SP140 nuclear body protein