SP100 antibody (AA 1-480)

Catalog No. ABIN520413

Cited in 2+ publications. The Mouse Polyclonal anti-SP100 antibody (ABIN520413) specifically detects SP100 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for SP100 antibody (AA 1-480) (ABIN520413)

Target: SP100 (SP100 Nuclear Antigen (SP100))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This SP100 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SP100 Antibody

Binding Specificity: AA 1-480

Purpose: Mouse polyclonal antibody raised against a full-length human SP100 protein.

Sequence: MAGGGGDLST RRLNECISPV ANEMNHLPAH SHDLQRMFTE DQGVDDRLLY DIVFKHFKRN KVEISNAIKK TFPFLEGLRD RDLITNKMFE DSQDSCRNLV PVQRVVYNVL SELEKTFNLP VLEALFSDVN MQEYPDLIHI YKGFENVIHD KLPLQESEEE EREERSGLQL SLEQGTGENS FRSLTWPPSG SPSHAGTTPP ENGLSEHPCE TEQINAKRKD TTSDKDDSLG SQQTNEQCAQ KAEPTESCEQ IAVQVNNGDA GREMPCPLPC DEESPEAELH NHGIQINSCS VRLVDIKKEK PFSNSKVECQ AQARTHHNQA SDIIVISSED SEGSTDVDEP LEVFISAPRS EPVINNDNPL ESNDEKEGQE ATCSRPQIVP EPMDFRKLST FRESFKKRVI GQDHDFSESS EEEAPAEASS GALRSKHGEK APMTSRSTST WRIPSRKRRF SSSDFSDLSN GEELQETCSS SLRRGSGKED

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SP100 (AAH11562.1, 1 a.a. ~ 480 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: No additive

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SP100 antibody (ABIN520413)

Wagenknecht, Reuter, Scherer, Reichel, Müller, Stamminger: "Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1." in: Viruses, Vol. 7, Issue 6, pp. 2884-907, (2015) (PubMed).

Full, Jungnickl, Reuter, Bogner, Brulois, Scholz, Stürzl, Myoung, Jung, Stamminger, Ensser: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).

Target Details for SP100

Target: SP100 (SP100 Nuclear Antigen (SP100))

Alternative Name: SP100

Background: Full Gene Name: SP100 nuclear antigen
Synonyms: DKFZp686E07254,FLJ00340,FLJ34579

Gene ID: 6672

Pathways: Retinoic Acid Receptor Signaling Pathway