SP100 antibody (AA 1-480)

Catalog No. ABIN948494

There are 3+ publications for this product available. The Mouse Polyclonal anti-SP100 antibody is suitable to detect SP100 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for SP100 antibody (AA 1-480) (ABIN948494)

Target: SP100 (SP100 Nuclear Antigen (SP100))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This SP100 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SP100 Antibody

Binding Specificity: AA 1-480

Purpose: Mouse polyclonal antibody raised against a full-length human SP100 protein.

Sequence: MAGGGGDLST RRLNECISPV ANEMNHLPAH SHDLQRMFTE DQGVDDRLLY DIVFKHFKRN KVEISNAIKK TFPFLEGLRD RDLITNKMFE DSQDSCRNLV PVQRVVYNVL SELEKTFNLP VLEALFSDVN MQEYPDLIHI YKGFENVIHD KLPLQESEEE EREERSGLQL SLEQGTGENS FRSLTWPPSG SPSHAGTTPP ENGLSEHPCE TEQINAKRKD TTSDKDDSLG SQQTNEQCAQ KAEPTESCEQ IAVQVNNGDA GREMPCPLPC DEESPEAELH NHGIQINSCS VRLVDIKKEK PFSNSKVECQ AQARTHHNQA SDIIVISSED SEGSTDVDEP LEVFISAPRS EPVINNDNPL ESNDEKEGQE ATCSRPQIVP EPMDFRKLST FRESFKKRVI GQDHDFSESS EEEAPAEASS GALRSKHGEK APMTSRSTST WRIPSRKRRF SSSDFSDLSN GEELQETCSS SLRRGSGKED

Cross-Reactivity: Human

Characteristics: Antibody reactive against mammalian transfected lysate.

Immunogen: SP100 (AAH11562.1, 1 a.a. ~ 480 a.a) full-length human protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-SP100 antibody (ABIN948494)

Full, Jungnickl, Reuter, Bogner, Brulois, Scholz, Stürzl, Myoung, Jung, Stamminger, Ensser: "Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity." in: PLoS pathogens, Vol. 10, Issue 1, pp. e1003863, (2014) (PubMed).

Adler, Tavalai, Müller, Stamminger: "Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100." in: The Journal of general virology, Vol. 92, Issue Pt 7, pp. 1532-8, (2011) (PubMed).

Tavalai, Adler, Scherer, Riedl, Stamminger: "Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle." in: Journal of virology, Vol. 85, Issue 18, pp. 9447-58, (2011) (PubMed).

Target Details for SP100

Target: SP100 (SP100 Nuclear Antigen (SP100))

Alternative Name: SP100

Background: Full Gene Name: SP100 nuclear antigen
Synonyms: DKFZp686E07254,FLJ00340,FLJ34579

Gene ID: 6672

Pathways: Retinoic Acid Receptor Signaling Pathway