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RPS6KA3 Products

(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008].

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Featured RPS6KA3 Categories

RPS6KA3 Antibodies

High quality antibodies with extensive validation data.

RPS6KA3 ELISA Kits

Reliable ELISA kits for a wide range of species.

RPS6KA3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPS6KA3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ICC, FACS, ELISA, WB
Validations
  • (2)
  • (5)
Cat. No. ABIN969386
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (5)
Cat. No. ABIN7270038
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application EIA, IF, WB
Validations
  • (5)
Cat. No. ABIN1108903
Quantity 0.1 mL
Datasheet Datasheet

Recommended RPS6KA3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380244
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380243
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380242
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended RPS6KA3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (2)
Cat. No. ABIN5570245
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093513
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133198
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RPS6KA3 products

Duda, Lonowski, Kofoed-Nielsen, Ibarra, Delay, Kang, Yang, Pruett-Miller, Bennett, Wandall, Davis, Hansen, Frödin: "High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs." in: Nucleic acids research, Vol. 42, Issue 10, pp. e84, (2014) (PubMed).

Czaplinska, Turczyk, Grudowska, Mieszkowska, Lipinska, Skladanowski, Zaczek, Romanska, Sadej: "Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration." in: Biochimica et biophysica acta, Vol. 1843, Issue 11, pp. 2461-70, (2014) (PubMed).

Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: "betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis." in: Molecular cell, Vol. 33, Issue 1, pp. 109-16, (2009) (PubMed).

Cho, Yao, Pugliese, Malakhova, Bode, Dong: "A regulatory mechanism for RSK2 NH(2)-terminal kinase activity." in: Cancer research, Vol. 69, Issue 10, pp. 4398-406, (2009) (PubMed).

Xiao, Wang, Zhou, Cao, Deng, Hu, Qu, Wen: "Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells." in: Acta biochimica et biophysica Sinica, Vol. 40, Issue 4, pp. 297-303, (2008) (PubMed).

Wissing, Jänsch, Nimtz, Dieterich, Hornberger, Kéri, Wehland, Daub: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, (2007) (PubMed).

Cho, Yao, Bode, Bergen, Madden, Oh, Ermakova, Kang, Choi, Shim, Dong: "RSK2 mediates muscle cell differentiation through regulation of NFAT3." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8380-92, (2007) (PubMed).

Zhang, Barclay, Alexander, Geldenhuys, Porter, Casson, Murphy: "Alternative splicing of the FGF antisense gene: differential subcellular localization in human tissues and esophageal adenocarcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 85, Issue 11, pp. 1215-28, (2007) (PubMed).

Pezzatini, Morbidelli, Solito, Paccagnini, Boanini, Bigi, Ziche: "Nanostructured HA crystals up-regulate FGF-2 expression and activity in microvascular endothelium promoting angiogenesis." in: Bone, Vol. 41, Issue 4, pp. 523-34, (2007) (PubMed).

Sheffler, Kroeze, Garcia, Deutch, Hufeisen, Leahy, Brüning, Roth: "p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 12, pp. 4717-22, (2006) (PubMed).

Synonyms and alternative names related to RPS6KA3

ribosomal protein S6 kinase A3 (RPS6KA3), ribosomal protein S6 kinase polypeptide 3 (Rps6ka3), ribosomal protein S6 kinase A3 (Rps6ka3), ribosomal protein S6 kinase, polypeptide 3b (rps6ka3b), CLS, HU-3, ISPK-1, MAPKAPK1B, MPK-9, MRX19, p90-RSK2, pp90RSK2, RGD1563860, RSK, RSK2, Rsk2, S6K-alpha3, zgc:158386

Protein level used designations for RPS6KA3

  • MAP kinase-activated protein kinase 1b
  • MAPK-activated protein kinase 1b
  • MAPKAP kinase 1b
  • MAPKAPK-1b
  • RSK-2
  • S6K-alpha-3
  • insulin-stimulated protein kinase 1
  • p90-RSK 3
  • ribosomal S6 kinase 2
  • ribosomal protein S6 kinase alpha-3
  • 90 kDa ribosomal protein S6 kinase 3
  • p90RSK3
  • ribosomal protein S6 kinase 2
  • ribosomal protein S6 kinase polypeptide 3
  • ribosomal protein S6 kinase a, polypeptide 3b
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3
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