Ricin Products
(Ricin)
Categories
Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D- galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).
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Recommended Ricin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Ricinus communis
Application
ELISA
Validations
Cat. No.
ABIN236276
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Ricinus communis
Application
ELISA
Validations
Cat. No.
ABIN1830156
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Ricinus communis
Application
ELISA, WB
Validations
Cat. No.
ABIN480071
Quantity
500 μg
Datasheet
Datasheet
Recommended Ricin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Ricinus communis
Source
Yeast
Validations
Cat. No.
ABIN1667688
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Ricin products
: "A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation." in: The Biochemical journal, Vol. 436, Issue 2, pp. 371-85, (2011) (PubMed).Synonyms and alternative names related to Ricin
ricin (LOC8261245)Protein level used designations for Ricin
- proricin A chain
- ricin
- ricin E beta chain
- ricin homolog, truncated
Did you look for something else?
- RIC8B
- RIC3
- Ribulose Bisphosphate Carboxylase Small Chain, Chloroplastic
- Ribosome-Recycling Factor (Frr)
- Ribosomal-Ubiquitin Fusion Protein Ubi3
- Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3
- Ribosomal Protein S3A
- Ribosomal Protein L5
- Ribosomal Protein L4
- Ribosomal Protein L12
- Ribose 5-Phosphate Isomerase A
- Ribophorin II
- Ribonucleoprotein
- Ribonuclease T1
- Ribonuclease K
- Ribonuclease H1
- Ribonuclease BN
- Ribonuclease A8
- Ribonuclease A6
- Ribonuclease 3
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