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anti-Mouse (Murine) EPH Receptor B6 Antibodies:
anti-Human EPH Receptor B6 Antibodies:
anti-Rat (Rattus) EPH Receptor B6 Antibodies:
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Human Polyclonal EPH Receptor B6 Primary Antibody for WB - ABIN1881301
Islam, Loizides, Fialkovich, Grand, Montgomery: Developmental expression of Eph and ephrin family genes in mammalian small intestine. in Digestive diseases and sciences 2010
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Human Polyclonal EPH Receptor B6 Primary Antibody for IHC (p), WB - ABIN391928
Freywald, Sharfe, Rashotte, Grunberger, Roifman: The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses. in The Journal of biological chemistry 2003
Show all 5 Pubmed References
Human Monoclonal EPH Receptor B6 Primary Antibody for IHC, ELISA - ABIN966077
Matsuoka, Obama, Kelly, Matsui, Nakamoto: Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration. in The Journal of biological chemistry 2005
Show all 2 Pubmed References
Human Monoclonal EPH Receptor B6 Primary Antibody for IHC, ELISA - ABIN969479
Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases. in Journal of cell science 2006
Show all 2 Pubmed References
Human Monoclonal EPH Receptor B6 Primary Antibody for IHC (p), ELISA - ABIN560773
Bailey, Kulesa: Dynamic interactions between cancer cells and the embryonic microenvironment regulate cell invasion and reveal EphB6 as a metastasis suppressor. in Molecular cancer research : MCR 2014
Colitis significantly downregulates Ephb6 expression in the neurons of the spinal dorsal horn.
T-cell development in EphB6 knockout mice
EphB6 is pivotal in T cell function as shown by its null mutation
Low EPHB6 expression is associated with prostate cancer metastasis.
Enhanced EphB6 expression was significantly associated with Thyroid Lesions.
EphB6 protein may be used as a new marker for prognosis for tongue squamous cell carcinoma.
EphB6 is a new biomarker for distinguishing high- and low-grade ovarian serous carcinoma, and may be a potential prognostic marker in ovarian serous carcinomas.
EphB6 also interacts with the Hsp90 chaperone (show HSP90 Antibodies).
These findings implicate EphB6 as a negative regulator of EphA2 (show EPHA2 Antibodies) oncogenic signaling.
We demonstrate that EphB6 reexpression forces metastatic melanoma cells to deviate from the canonical migration pattern observed in the chick embryo transplant model
Results suggest that erythropoietin (show EPO Antibodies)-producing hepatocyte (Eph) receptor B6 (EphB6) may represent a useful tissue biomarker for the prediction of survival rate in colorectal cancers (CRCs).
Studies clearly demonstrate an inverse relationship between the levels of phospho-ERK (show EPHB2 Antibodies) and the abundance of cadherin 17, beta-catenin (show CTNNB1 Antibodies) and phospho-GSK3beta (show GSK3b Antibodies) in EPHB6-expressing MDA-MB-231 cells.
Data found significant correlations between ephA2 (show EPHA2 Antibodies), ephA4 (show EPHA4 Antibodies), ephA7 (show EPHA7 Antibodies), ephB4 (show EPHB4 Antibodies), and ephB6 and overall and/or recurrence-free survival in large microarray datasets.
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Chicken embryo kinase 9
, EPH-like kinase 9
, ephrin type-B receptor 5
, ephrin receptor EphB6
, ephrin type-B receptor 6
, EPH receptor B6
, ephrin type-B receptor 6-like
, chicken eph/elk receptor-like protein
, ephrin type A receptor
, tyrosine-protein kinase-defective receptor EPH-6
, human kinase-defective Eph-family receptor protein