Browse our anti-PDGFRA (PDGFRA) Antibodies

Full name:: anti-Platelet-Derived Growth Factor Receptor, alpha Polypeptide Antibodies (PDGFRA)

On www.antibodies-online.com are 569 Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies from 30 different suppliers available. Additionally we are shipping PDGFRA Kits (68) and PDGFRA Proteins (42) and many more products for this protein. A total of 707 PDGFRA products are currently listed.

Synonyms:: AI115593, APDGFR, CD140A, PDGFACE, PDGFR, PDGFR-2, PDGFR-A, PDGFR2, RHEPDGFRA

list all antibodies	Gene Name	GeneID	UniProt
	PDGFRA	18595	P26618
	PDGFRA	25267	P20786
	PDGFRA	5156	P16234
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Most Popular Reactivities for anti-PDGFRA (PDGFRA) Antibodies

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anti-Mouse (Murine) PDGFRA Antibodies:

anti-Rat (Rattus) PDGFRA Antibodies:

anti-Human PDGFRA Antibodies:

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Relevant Pathways for anti-PDGFRA Antibodies

Platelet-derived growth Factor Receptor Signaling

More product categories related to PDGFRA Antibody

Top referenced anti-PDGFRA Antibodies

Human Monoclonal PDGFRA Primary Antibody for FACS, IP - ABIN4900645 : Velghe, Van Cauwenberghe, Polyansky, Chand, Montano-Almendras, Charni, Hallberg, Essaghir, Demoulin: PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations. in Oncogene 2014 (PubMed)
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Human Monoclonal PDGFRA Primary Antibody for FACS - ABIN4898823 : Uosaki, Andersen, Shenje, Fernandez, Christiansen, Kwon: Direct contact with endoderm-like cells efficiently induces cardiac progenitors from mouse and human pluripotent stem cells. in PLoS ONE 2012 (PubMed)
Show all 4 Pubmed References
Mouse (Murine) Monoclonal PDGFRA Primary Antibody for FACS - ABIN1176995 : Fruttiger, Calver, Krüger, Mudhar, Michalovich, Takakura, Nishikawa, Richardson: PDGF mediates a neuron-astrocyte interaction in the developing retina. in Neuron 1997 (PubMed)
Show all 3 Pubmed References
Human Polyclonal PDGFRA Primary Antibody for WB - ABIN271391 : Zheng, Ishii, Tokunaga, Hamashima, Shen, Zhao, Ishizawa, Fujimori, Nabeshima, Mori, Kondo, Sasahara: Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved. in Journal of neuroscience research 2010 (PubMed)
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Human Monoclonal PDGFRA Primary Antibody for FACS - ABIN4898820 : Craft, Rockel, Nartiss, Kandel, Alman, Keller: Generation of articular chondrocytes from human pluripotent stem cells. in Nature biotechnology 2015 (PubMed)
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Human Polyclonal PDGFRA Primary Antibody for PLA, WB - ABIN518742 : Moroncini, Grieco, Nacci, Paolini, Tonnini, Pozniak, Cuccioloni, Mozzicafreddo, Svegliati, Angeletti, Kazlauskas, Avvedimento, Funaro, Gabrielli: Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis. in Arthritis & rheumatology (Hoboken, N.J.) 2015 (PubMed)
Human Monoclonal PDGFRA Primary Antibody for PLA, ELISA - ABIN518743 : Dugas, Cuellar, Scholze, Ason, Ibrahim, Emery, Zamanian, Foo, McManus, Barres: Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. in Neuron 2010 (PubMed)
Human Polyclonal PDGFRA Primary Antibody for IF (p), IHC (p) - ABIN726620 : Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious. in International journal of clinical and experimental pathology 2015 (PubMed)
Human Polyclonal PDGFRA Primary Antibody for IHC (p), WB - ABIN392024 : Wilczynski, Chen, Chen, Howell, Shively, Alberts: Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers. in Human pathology 2005 (PubMed)
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Human Monoclonal PDGFRA Primary Antibody for Func, FACS - ABIN2688972 : Bazenet, Kazlauskas: The PDGF receptor alpha subunit activates p21ras and triggers DNA synthesis without interacting with rasGAP. in Oncogene 1994 (PubMed)

More Antibodies against PDGFRA Interaction Partners

Mouse (Murine) Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) interaction partners

PDGFRA is not essential for the derivation and maintenance of extraembryonic endoderm stem (XEN) cell lines .
loss of Pdgfra in endothelial-derived (show MED28 Antibodies) mesenchyme in the outflow tract endocardial cushions leads to a secondary defect in neural crest migration during development.
Investigated the developmental process of mesenchymal stem cells (MSCs) in embryos using the gene Pdgfra as a marker. We traced cells expressing Pdgfra and other genes (brachyury (show TBX1 Antibodies), Sox1 (show SOX1 Antibodies) and Pmx1 (show PRRX1 Antibodies)) in various mutant embryos until the adult stage. Embryonic MSCs emerge in waves and almost all adult bone marrow MSCs and white adipose tissue MSCs originate from mesoderm and embryonic Pdgfralpha-positive cells.
PDGFRalpha/PDGFRbeta signaling balance determines progenitor commitment to beige (show LYST Antibodies) (PDGFRalpha) or white (PDGFRbeta) adipogenesis.
Spreading of PDGFR-alpha-deficient lung fibroblasts was insensitive to increased rigidity, and their migration was not reduced by Rac1 (show RAC1 Antibodies)-guanine exchange factor (GEF (show ARHGEF2 Antibodies))-inhibition. PDGFR-alpha-expressing fibroblasts migrated toward stiffer regions within two-dimensional substrates by increasing migrational persistence (durotaxis).
Histone H3.3K27M and Trp53 (show TP53 Antibodies) loss and PDGFRA overexpression accelerates disease onset and increases tumor invasion.
The diabetes-induced increase in PDGFRalpha+ cells may be mediated by FOXO3 up-regulation via the inhibition of the PI3K/Akt signaling pathway in STZ-induced diabetic mice.
Constitutive activation of PDGFRalpha leads to expansion of cartilage underlying the coronal sutures, which contribute to suture closure through endochondral ossification, in a process regulated in part by PI3K/AKT (show AKT1 Antibodies) signaling.
OLIG2 (show OLIG2 Antibodies) modulates growth factor signaling in two distinct populations of glioma stem cells, characterized by expression of either the epidermal growth factor receptor (EGFR (show EGFR Antibodies)) or platelet-derived growth factor receptor alpha.
Conditional knockout of Pdgfra in Pdgfra-expressing tissues in mouse embryos at different embryonic days (E9.5 and E10.5) resulted in multiple developmental anomalies of the frontonasal region, the cranium and the abdominal wall musculature. Furthermore, the day at which the Pdgfra is deleted influences the repertoire of the anomalies of the conditional knockout embryos.

Rabbit Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) interaction partners

High PDGFR (show PDGFRB Antibodies) expression is associated with retinal neovascularization.

Human Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) interaction partners

PDGFRA D842V mutant binds imatinib with lower affinity with respect to wild-type structure, showing higher stability during the interaction with other type I TKIs (like crenolanib).
Altered SK3 channel expression observed in PDGFRalpha(+) cells in UPJ obstruction suggests that the impairment of SK3 activity across the UPJ may perturb upper urinary tract peristalsis in this urological condition
None of the 16 analyzable tumors showed mutations in PDGFRA. Thus, PDGFRA mutations probably do not play an important role in the development of sporadic lipomas of the intestines
Whole transcriptome sequencing followed by pathway analysis indicated that STXBP4 (show STXBP4 Antibodies) is involved in functional gene networks that regulate cell growth, proliferation, cell death, and survival in cancer. Platelet-derived growth factor receptor alpha (PDGFRalpha) was a key downstream mediator of STXBP4 (show STXBP4 Antibodies) function. In line with this, shRNA mediated STXBP4 (show STXBP4 Antibodies) and PDGFRA knockdown suppressed tumor growth in soft-agar and xenograft ...
We report a unique case of an SDH (show SARDH Antibodies)-deficient GIST case with an activating PDGFRA mutation. Oncogenic mutations in GIST are generally mutually exclusive; however documented exceptions exist which may have diagnostic and therapeutic implications.
Case Report: concurrent development of myeloproliferative hypereosinophilic syndrome and lymphomatoid papulosis associated with FIP1L1 (show FIP1L1 Antibodies)-PDGFRA gene fusion.
Our results suggest that PDGFRalpha overexpression in HCC (show FAM126A Antibodies) is a prognostic marker independent of adjacent non-tumor site liver fibrosis status.
PDGFRalpha/PDGFRbeta signaling balance determines progenitor commitment to beige (show LYST Antibodies) (PDGFRalpha) or white (PDGFRbeta) adipogenesis.
overview of primary cilia-mediated regulation of receptor tyrosine kinase (show RET Antibodies) (RTK- PDGFRa and PDGFRb (show PDGFRB Antibodies)) and transforming growth factor beta (TGF-beta) signaling [review]
PDGFRA mutation, but not amplification is associated with older age in pediatric high-grade glioma.

PDGFRA Antigen Profile

Antigen Summary

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Alternative names and synonyms associated with PDGFRA

platelet derived growth factor receptor alpha (PDGFRA) antibody
platelet derived growth factor receptor, alpha polypeptide (Pdgfra) antibody
platelet derived growth factor receptor alpha (Pdgfra) antibody
platelet-derived growth factor receptor, alpha polypeptide L homeolog (pdgfra.L) antibody
platelet-derived growth factor receptor, alpha polypeptide (PDGFRA) antibody

AI115593 antibody
APDGFR antibody
CD140A antibody
PDGFACE antibody
PDGFR antibody
PDGFR-2 antibody
PDGFR-A antibody
PDGFR2 antibody
RHEPDGFRA antibody

Protein level used designations for PDGFRA

platelet-derived growth factor receptor, alpha polypeptide , alpha-type platelet-derived growth factor receptor-like , Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha) , CD140 antigen-like family member A , PDGF alpha chain , PDGF-R-alpha , PDGFR-alpha , alpha-type platelet-derived growth factor receptor , platelet-derived growth factor alpha receptor , platelet-derived growth factor receptor alpha , alpha platelet-derived growth factor receptor , CD140a antigen , PDGFRA/BCR fusion , platelet-derived growth factor receptor 2 , rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein , tyrosine kinase PDGFR

GENE ID	SPECIES
100059815	Equus caballus
100218386	Taeniopygia guttata
100412331	Callithrix jacchus
100431735	Pongo abelii
100464991	Ailuropoda melanoleuca
18595	Mus musculus
25267	Rattus norvegicus
380245	Xenopus laevis
100343006	Oryctolagus cuniculus
5156	Homo sapiens
442860	Canis lupus familiaris
407607	Sus scrofa
282301	Bos taurus
395509	Gallus gallus

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Show all anti-Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) Antibodies with Pubmed References