Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Ras-specific guanine nucleotide-releasing factor, CDC25 homolog
, Ras-specific nucleotide exchange factor CDC25
, guanine nucleotide exchange factor
, guanine nucleotide-releasing factor 1
, guanine nucleotide-releasing factor, 55 kD
, guanine nucleotide-releasing protein
, ras-specific guanine nucleotide-releasing factor 1
, GRF beta
, Ras guanine release factor beta
, guanine nucleotide releasing factor 1
, ras-specific nucleotide exchange factor CDC25
, P140 RAS-GRF
, Ras protein-specific guanine nucleotide-releasing factor 1
, ras-specific guanine nucleotide-releasing factor 1-like