Scd3 Protein (AA 1-359) (His tag)
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- Target
- Scd3 (SCD3) (Stearoyl-Coenzyme A Desaturase 3 (SCD3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-359
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Scd3 protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Scd3 Protein expressed in mammalian cells.
- Sequence
- MPGHLLQEEM TPSYTTTTTI TAPPSGSLQN GREKVKTVPL YLEEDIRPEM KEDIYDPTYQ DEEGPPPKLE YVWRNIILMA LLHVGALYGI TLVPSCKLYT CLFAFVYYVI SIEGIGAGVH RLWSHRTYKA RLPLRIFLII ANTMAFQNDV YEWARDHRAH HKFSETHADP HNSRRGFFFS HVGWLLVRKH PAVKEKGGKL DMSDLKAEKL VMFQRRYYKP GILLMCFILP TLVPWYCWGE TFLNSFYVAT LLRYAVVLNA TWLVNSAAHL YGYRPYDKNI DPRQNALVSL GSMGEGFHNY HHAFPYDYSA SEYRWHINFT TFFIDCMAAL GLAYDRKRVS KATVLARIKR TGDGSHKSG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Scd3 (SCD3) (Stearoyl-Coenzyme A Desaturase 3 (SCD3))
- Alternative Name
- Scd3
- Background
- Acyl-CoA desaturase 3 (EC 1.14.19.-) (Delta(9)-desaturase 3) (Delta-9 desaturase 3) (Fatty acid desaturase 3) (Palmitoyl-CoA desaturase) (Stearoyl-CoA desaturase 3),FUNCTION: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA (PubMed:16443825, PubMed:26098370). Has a strong preference for saturated fatty acids with chain lengths of 14 or 16 carbon atoms (C14:0 and C16:0), and has only very low activity with stearatate (C18:0) (PubMed:16443825, PubMed:26098370). Required for the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity). {ECO:0000250|UniProtKB:O00767, ECO:0000269|PubMed:16443825, ECO:0000269|PubMed:26098370}.
- Molecular Weight
- 41.4 kDa
- UniProt
- Q99PL7
- AlphaFold
- Q99PL7
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