SERPINA1 Proteins
(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
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36 results :
SERPINA1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SERPINA1
Origin: Mouse
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
1 image
SERPINA1
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
SERPINA1
Origin: Rat
Host: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
SERPINA1
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINA1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINA1
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SERPINA1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our SERPINA1 Proteins
: "Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 11, pp. 2477-2489, (2017) (PubMed).: "Erratum to: Rectocutaneous fistula with transmigration of the suture: a rare delayed complication of vault fixation with the sacrospinous ligament." in: International urogynecology journal, Vol. 27, Issue 3, pp. 505, (2016) (PubMed).
: "LaCyTools: A Targeted Liquid Chromatography-Mass Spectrometry Data Processing Package for Relative Quantitation of Glycopeptides." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2198-210, (2016) (PubMed).
: "Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase." in: American journal of respiratory cell and molecular biology, Vol. 54, Issue 3, pp. 341-9, (2016) (PubMed).
: "Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification." in: Circulation research, Vol. 117, Issue 9, pp. 758-69, (2015) (PubMed).
: "The BLT1 Inhibitory Function of ?-1 Antitrypsin Augmentation Therapy Disrupts Leukotriene B4 Neutrophil Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 8, pp. 3628-41, (2015) (PubMed).
: "Enhanced recognition of plasma proteins in a non-native state by complement C3b. A possible clearance mechanism for damaged proteins in blood." in: Molecular immunology, Vol. 64, Issue 1, pp. 55-62, (2015) (PubMed).
: "Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 1, pp. L80-7, (2014) (PubMed).
: "Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 3, pp. 1220-30, (2014) (PubMed).
Aliases for SERPINA1 Proteins
serpin family A member 3 (SERPINA3) Proteinsalpha-1-antiproteinase F precursor (LOC100008973) Proteins
serpin family A member 1 (SERPINA1) Proteins
alpha-1-antitrypsin (LOC100328621) Proteins
calumenin (CALU) Proteins
serpin family A member 1 (Serpina1) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog (serpina1.S) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) Proteins
SH2B adaptor protein 2 (Sh2b2) Proteins
calumenin (Calu) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) Proteins
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog (serpina1.L) Proteins
A1A Proteins
A1AT Proteins
AACT Proteins
AAT Proteins
ACT Proteins
alpha-1-PI Proteins
alpha1AT Proteins
Aps Proteins
GIG25 Proteins
MGC64429 Proteins
PI Proteins
Pi Proteins
PI1 Proteins
PRO2275 Proteins
serpina1d Proteins
SERPINA3-5 Proteins
Spi1 Proteins
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- SERPINA3K Proteins
- SERPINA3N Proteins
- SERPINA4 Proteins
- SERPINA5 Proteins
- SERPINA6 Proteins
- SERPINA7 Proteins
- SERPINA9 Proteins
- SERPINB1 Proteins
- SERPINB10 Proteins
- SERPINB12 Proteins
- SERPINB13 Proteins
- SERPINB2 Proteins
- SERPINB3 Proteins
- SERPINB4 Proteins
- SERPINB5 Proteins
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