Goat anti-Human IgG (Heavy & Light Chain) Antibody (Agarose Beads)

Catalog No. ABIN233741

Supplier Product No.: 209-1150

Quick Overview for Goat anti-Human IgG (Heavy & Light Chain) Antibody (Agarose Beads) (ABIN233741)

Target: IgG

Clonality: Polyclonal

Conjugate: Agarose Beads

Application: Immunoprecipitation (IP)

Isotype: IgG

Product Details

Binding Specificity: Heavy & Light Chain

Reactivity: Human

Host: Goat

Supplier Product No.: 209-1150

Supplier: Rockland

Purpose: Human IgG Antibody Agarose

Cross-Reactivity (Details): Sufficient antibody capacity is provided to bind a minimum of 5 mg of pure Human IgG.

Characteristics: CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

Purification: This product is an IgG fraction antibody coupled to activated agarose.

Application Details

Application Notes: Application Note: Anti-Human IgG Agarose Conjugate is useful for immunoprecipitation and other immunological assays. Immunoprecipitation Dilution: User Optimized

Restrictions: For Research Use only

Handling

Concentration: 10 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

, Preservative:0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store vial at 4° C prior to opening. DO NOT FREEZE.

Expiry Date: 12 months

Target Details

Target: IgG

Target Type: Antibody

Background: It is a protein complex composed of four peptide chains - two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers. Each IgG has two antigen binding sites. Representing approximately 75 % of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition.