Rat anti-Mouse IgE Antibody

Catalog No. ABIN2474306

Quick Overview for Rat anti-Mouse IgE Antibody (ABIN2474306)

Target: IgE

Clonality: Monoclonal

Application: ELISA

Clone: LO-ME-2

Isotype: IgG2a

Product Details

Reactivity: Mouse

Host: Rat

Specificity: This antibody reacts with the epsilon heavy chain of mouse IgE. No cross reactivity is seen with other mouse isotypes, as tested in an ELISA.

Characteristics: Purified IgG

Purification: Purified

Immunogen: Purified IgE from Balb/c mice

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

References

Kikuchi, Takai, Kuhara, Ota, Kato, Hatanaka, Ichikawa, Tokura, Akiba, Mitsuishi, Ikeda, Okumura, Ogawa: "Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 3, pp. 1609-17, (2006) (PubMed).

Peebles, Hashimoto, Sheller, Moore, Morrow, Ji, Elias, Goleniewska, Oneal, Mitchell, Graham, Zhou: "Allergen-induced airway hyperresponsiveness mediated by cyclooxygenase inhibition is not dependent on 5-lipoxygenase or IL-5, but is IL-13 dependent." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 12, pp. 8253-9, (2005) (PubMed).

Hashimoto, Sheller, Morrow, Collins, Goleniewska, ONeal, Zhou, Ji, Mitchell, Graham, Peebles: "Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 1, pp. 525-32, (2004) (PubMed).

Target Details

Target: IgE

Gene ID: 380792

UniProt: P06336