Rabbit anti-Mouse IgG1, kappa Antibody

Catalog No. ABIN2690376

Quick Overview for Rabbit anti-Mouse IgG1, kappa Antibody (ABIN2690376)

Target: IgG1, kappa

Clonality: Polyclonal

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Isotype: IgG

Product Details

Reactivity: Mouse

Host: Rabbit

Purification: Purified by Protein A.

Application Details

Application Notes: WB 1:500-2000
ELISA 1:500-2000
IHC-P 1:500-2000
IHC-F 1:500-2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

References

Ahn, Shin, Lee, Kang, Seok, Kang, Jeung: "Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 3697-703, (2017) (PubMed).

Target Details

Target: IgG1, kappa

Alternative Name: IgG1, Kappa Light Chain

Background:

Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.