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Mouse anti-Human IgG (Fab Region) Antibody (PE)

FACS Monoclonal 4A11 IgG1 kappa PE
Catalog No. ABIN349709
  • Target See all IgG products
    IgG
    Binding Specificity
    • 2297
    • 481
    • 406
    • 127
    • 125
    • 117
    • 63
    • 29
    • 28
    • 28
    • 21
    • 9
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Fab Region
    Reactivity
    • 705
    • 674
    • 561
    • 434
    • 393
    • 232
    • 199
    • 172
    • 137
    • 137
    • 112
    • 105
    • 103
    • 95
    • 82
    • 61
    • 43
    • 28
    • 27
    • 16
    • 15
    • 10
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 1701
    • 1480
    • 540
    • 250
    • 122
    • 101
    • 38
    • 32
    • 21
    • 15
    • 13
    • 11
    • 11
    Mouse
    Clonality
    • 3292
    • 177
    • 16
    • 1
    Monoclonal
    Conjugate
    • 594
    • 402
    • 399
    • 355
    • 272
    • 249
    • 221
    • 117
    • 84
    • 69
    • 64
    • 61
    • 58
    • 54
    • 50
    • 46
    • 43
    • 40
    • 40
    • 39
    • 38
    • 36
    • 35
    • 35
    • 32
    • 31
    • 31
    • 30
    • 29
    • 29
    • 29
    • 29
    • 29
    • 28
    • 28
    • 28
    • 28
    • 28
    • 28
    • 28
    • 27
    • 27
    • 26
    • 26
    • 25
    • 21
    • 20
    • 19
    • 17
    • 17
    • 15
    PE
    Application
    • 1990
    • 1977
    • 1815
    • 1746
    • 946
    • 875
    • 868
    • 442
    • 376
    • 233
    • 233
    • 148
    • 98
    • 75
    • 57
    • 47
    • 37
    • 33
    • 29
    • 28
    • 25
    • 20
    • 15
    • 11
    • 9
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purpose
    Anti-Hu IgG (Fab) PE
    Specificity
    The mouse monoclonal antibody 4A11 reacts with Fab fragment of human IgG. This antibody detects Fab fragments regardless light chain type.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Purified human IgG.
    Clone
    4A11
    Isotype
    IgG1 kappa
  • Application Notes
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    No reconstitution is necessary.
    Concentration
    0.1 mg/mL
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Avoid prolonged exposure to light.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    IgG
    Abstract
    IgG Products
    Target Type
    Antibody
    Background
    Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.,Immunoglobulin G Fab fragment
    Molecular Weight
    150 kDa
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