Mouse anti-Chicken IgA (Chain alpha) Antibody

Catalog No. ABIN371388

Quick Overview for Mouse anti-Chicken IgA (Chain alpha) Antibody (ABIN371388)

Target: IgA

Clonality: Monoclonal

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: A-1

Isotype: IgG2b

Product Details

Binding Specificity: Chain alpha

Reactivity: Chicken

Host: Mouse

Purification: Purified

Application Details

Application Notes: ELISA. Flow Cytometry. Immunofluorescence. Immunohistochemistry on Frozen Sections.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.

Target Details

Target: IgA

Target Type: Antibody

Background: Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.Synonyms: Chicken Immunoglobulin A

Molecular Weight: 160 kDa