Recombinant Rabbit anti-Mouse IgG Antibody (Acridinium ester)

Catalog No. ABIN7488628

Quick Overview for Recombinant Rabbit anti-Mouse IgG Antibody (Acridinium ester) (ABIN7488628)

Target: IgG

Antibody Type: Recombinant Antibody

Clonality: Chimeric

Conjugate: Acridinium ester

Application: Magnetism Particulate Chemiluminescence Immunoassay (MPCLIA)

Grade: MALS verified

Isotype: IgG

Product Details

Reactivity: Mouse

Host: Rabbit

Purpose: Anti-Mouse IgG-Acridine ester (MALS verified)

Immunogen: Anti-Mouse IgG-Acridine ester is a chimeric monoclonal antibody recombinantly expressed from human 293 cells(HEK293), which combines the variable region of a mousemonoclonal antibody with rabbit IgG constant domain.

Application Details

Application Notes: Chemiluminescence immunoassay (CLIA) is a much more effective measurement with the advantages of high sensitivity, uniformity and broad dynamic range. However, in traditional chemiluminescent immunoassay (CLIA),microplate was applied to immobilize antigen or antibody by physical absorption, which holds a negative effect on the perfor-mance of assay because of the low specific surface area of micro-plate. The use of micromagnetic particles (MMPs) have proven to be a support for addressing the shortage of traditional CLIA mentioned above The chemiluminescent immunoassay is a technique used for disease diagnosis, drug development, chemical reaction monitoring, and many other applications. The MMPs-based chemiluminescence immunoassays could improve the surface area for immobilization, capture efficiency and accuracy of the assay, thus obtaining higher sensitivity and shorter analysis time.

Comment:

Acridine ester, can react with the primary amino group of protein. Under alkaline conditions, NHS is replaced as the leaving group, and the protein forms a stable amide bond with acridine ester.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: -20 °C

Storage Comment: -20°C, avoid light

Target Details

Target: IgG

Target Type: Antibody