Recombinant Rabbit anti-Human IgD Antibody
Quick Overview for Recombinant Rabbit anti-Human IgD Antibody (ABIN7828298)
Target
Antibody Type
Clonality
Application
Clone
Isotype
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Reactivity
- Human
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Host
- Rabbit
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Purpose
- Recombinant Human IgD Monoclonal Antibody
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Purification
- Protein A purified
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Immunogen
- Recombinant human Human IgD fragment
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Application Notes
- WB 1:500-1:1000,IHC 1:50,IF 1:50
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Expiry Date
- 12 months
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- IgD
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Target Type
- Antibody
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Background
- IGHD,IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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Molecular Weight
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Calculated MW: 42 kDa
Observed MW: 75 kDa The actual band is not consistent with the expectation.
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UniProt
- P01880
Target
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