Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Recombinant Rabbit anti-Human IgD Antibody

WB, IF, IHC Monoclonal A258 IgG Recombinant Antibody unconjugated
Catalog No. ABIN7828298
$394.68
Plus shipping costs $50.00
50 μL
Shipping to: United States
Delivery in 11 to 14 Business Days

Quick Overview for Recombinant Rabbit anti-Human IgD Antibody (ABIN7828298)

Target

IgD

Antibody Type

Recombinant Antibody

Clonality

  • 29
  • 28
Monoclonal

Application

  • 30
  • 25
  • 12
  • 10
  • 7
  • 7
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Clone

A258

Isotype

IgG, kappa
  • Reactivity

    • 36
    • 16
    • 6
    Human

    Host

    • 20
    • 15
    • 10
    • 8
    • 5
    Rabbit

    Purpose

    Recombinant Human IgD Monoclonal Antibody

    Purification

    Protein A purified

    Immunogen

    Recombinant human Human IgD fragment
  • Application Notes

    WB 1:500-1:1000,IHC 1:50,IF 1:50

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    Expiry Date

    12 months
  • Target

    IgD

    Target Type

    Antibody

    Background

    IGHD,IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    Molecular Weight

    Calculated MW: 42 kDa

    Observed MW: 75 kDa The actual band is not consistent with the expectation.

    UniProt

    P01880
You are here:
Chat with us!