Recombinant Rabbit anti-Human lambda (full length), (Light Chain) Antibody

Catalog No. ABIN7879495

Quick Overview for Recombinant Rabbit anti-Human lambda (full length), (Light Chain) Antibody (ABIN7879495)

Target: lambda

Antibody Type: Recombinant Antibody

Clonality: Monoclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LLC-3774R

Isotype: IgG

Product Details

Binding Specificity: full length, Light Chain

Reactivity: Human

Host: Rabbit

Purpose: Recombinant Lambda Light Chain Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human IGL protein was used as the immunogen for the recombinant Lambda Light Chain antibody.

Application Details

Application Notes: Optimal dilution of the recombinant Lambda Light Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Lambda Light Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: lambda

Background: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01701, P01842