SPATA13 Proteins

(Spermatogenesis Associated 13 (SPATA13))

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

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SPATA13 Protein (AA 1-652) (His tag)

custom-made SPATA13 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant SPATA13 Protein, UniprotID Q96N96

3 images

Catalog No. ABIN7555602

Details

SPATA13 Protein (AA 1-656) (His tag)

custom-made SPATA13 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Spata13 Protein, UniprotID Q5DU57

3 images

Catalog No. ABIN7563812

Details

SPATA13 Protein (AA 1-656) (Strep Tag)

custom-made SPATA13 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3135187

Details

SPATA13 Protein (AA 1-652) (Strep Tag)

custom-made SPATA13 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3095624