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Browse our anti-RUVBL2 (RUVBL2) Antibodies

Full name:: anti-RuvB-Like 2 (E. Coli) Antibodies (RUVBL2)

On www.antibodies-online.com are 79 RuvB-Like 2 (E. Coli) (RUVBL2) Antibodies from 20 different suppliers available. Additionally we are shipping RUVBL2 Proteins (10) and and many more products for this protein. A total of 96 RUVBL2 products are currently listed.

Synonyms:: AAEL010341, cgi-46, ecp51, INO80J, MGC52995, MGC69398, mp47, p47, rept, Reptin, RUVBL2, rvb2, TIH2, tip48, tip49b, wu:fi25f01, xReptin, zreptin

list all antibodies	Gene Name	GeneID	UniProt
	RUVBL2	10856	Q9Y230
	RUVBL2	20174	Q9WTM5
	RUVBL2	292907
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Top referenced anti-RUVBL2 Antibodies

Human Polyclonal RUVBL2 Primary Antibody for ELISA, WB - ABIN544685 : Wood, McMahon, Cole: An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc. in Molecular cell 2000 (PubMed)
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Human Polyclonal RUVBL2 Primary Antibody for IF, WB - ABIN524254 : Maslon, Hrstka, Vojtesek, Hupp: A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin. in Journal of molecular biology 2010 (PubMed)
Cow (Bovine) Polyclonal RUVBL2 Primary Antibody for IHC, WB - ABIN2779601 : Bauer, Chauvet, Huber, Usseglio, Rothbächer, Aragnol, Kemler, Pradel: Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity. in The EMBO journal 2000 (PubMed)
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More Antibodies against RUVBL2 Interaction Partners

Human RuvB-Like 2 (E. Coli) (RUVBL2) interaction partners

Reptin directly interacted with histone deacetylase 1 (HDAC1) as the critical mechanism driving non-small cell lung cancer (NSCLC) tumour progression. Pharmacological disruption of the Reptin/HDAC1 complex resulted in a substantial decrease in NSCLC cell proliferation and induced significant sensitisation to cisplatin.
These results suggest a role of Reptin and Pontin in Salivary gland cancer tumor progression and/or patient survival.
The interaction between RUVBL1/RUVBL2 and the U5 small nuclear ribonucleoprotein is mostly mediated by the previously uncharacterized factor ZNHIT2.
Mep1A is overexpressed in most hepatocellular carcinomas and induces tumor cell migration and invasion. Mep1A expression is regulated by Reptin, and Mep1A mediates Reptin-induced migration.
Reptin silencing did not affect the tyrosine phosphorylation of the insulin receptor nor of IRS1, but it enhanced the tyrosine phosphorylation of the p85 subunit of PI3K.
Overall, POLG interactome mapping identifies novel proteins which support mitochondrial biogenesis and a potential novel mitochondrial isoform of Ruvbl2.
The authors report that HIV-1 exploits the host factor RuvB-like 2 (RVB2) to balance relative expression of Gag and Env for efficient production of infectious virions.
by means of molecular docking approaches we first modeled the structures of hetero-hexameric TIP49 ( TIP49a and TIP49b )complexes with short ds-DNA fragments (20 base pairs with different GC content) within the central channel of hexameric ring
Data suggest that overexpression of Reptin in hepatocellular carcinoma (HCC) could be a factor of resistance to treatment.
RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils.
results reveal a novel mechanism for the control of NF-kappaB pathway by cytoplasmic Reptin
The results suggests that a potential mechanism for the role of RuvBL1-RuvBL2 in maintaining genome integrity is through controlling the cellular abundance of Fanconi anaemia core complex.
Reptin and Pontin oligomerization and activity are modulated through histone H3 N-terminal tail interaction.
these findings suggest that YY1-RuvBL1-RuvBL2 complexes could contribute to functions beyond transcription, and we show that YY1 and the ATPase activity of RuvBL2 are required for RAD51 foci formation during homologous recombination.
The Reptin is unable to bind with membrane-associated APPL proteins.
Anti-RuvBL1/2 antibody is a novel systemic scleroderma-related autoantibody associated with a unique combination of clinical features, including myositis overlap and diffuse cutaneous involvement.
Data suggest that reptin may prove to be a valuable target for prevention and treatment of renal cell carcinoma.
Data indicate that the RVB1/2 chromatin-remodeling complex is required for efficient Pol II recruitment and initiation at IFN-alpha-stimulated genes (ISGs) promoters and is recruited through interaction with the STAT2 transactivation domain.
We demonstrate that leukemogenic activity of MLL-AF9 requires RUVBL2 (RuvB-like 2), an AAA+ ATPase family member that functions in a wide range of cellular processes, including chromatin remodeling and transcriptional regulation.
Two coexisting conformations, compact and stretched, are revealed by analysis of cryo-electron microscopy structures of the RuvBL1-RuvBL2 complex.

Mouse (Murine) RuvB-Like 2 (E. Coli) (RUVBL2) interaction partners

Ruvbl2 has a role in the differentiation of neuroectoderm during early embryogenesis.
accumulating E2f1 progressively recruits a Pontin/Reptin complex to open the chromatin conformation at E2f target genes and amplifies the E2f transcriptional response.
Reptin plays a key role in maintaining the pluripotency of embryonic stem cells and in establishing the pluripotency during reprogramming of somatic cells by regulation of Oct4-mediated gene regulation
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.
We demonstrate that leukemogenic activity of MLL-AF9 requires RUVBL2 (RuvB-like 2), an AAA+ ATPase family member that functions in a wide range of cellular processes, including chromatin remodeling and transcriptional regulation.
A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity.
Ectopic expression of RUVBL2 decreases the levels of ARF, whereas knockdown of RUVBL2 results in a marked increase in ARF levels. In addition, RUVBL2 down-regulates the levels of p53 in an ARF-dependent manner.
Reptin, a chromatin-remodeling factor, is methylated at lysine 67 in hypoxic conditions by the methyltransferase G9a.
RuvBl2, which encodes an ATP-dependent DNA helicase, is specifically detected in the spermatocytes and spermatids of the adult testis as well as in primordial germ cells.
RUVBL2 plays an important role in insulin-stimulated GLUT4 translocation through its interaction with AS160

Zebrafish RuvB-Like 2 (E. Coli) (RUVBL2) interaction partners

the Reptin-Lrrc6/Seahorse complex is involved in dynein arm formation.
the reptin/pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway

Xenopus laevis RuvB-Like 2 (E. Coli) (RUVBL2) interaction partners

xPontin and xReptin are essential genes regulating cell proliferation in early Xenopus embryogenesis through interaction with c-Myc

RUVBL2 Antigen Profile

Antigen Summary

This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Alternative names and synonyms associated with RUVBL2

RuvB like AAA ATPase 2 (RUVBL2) antibody
RuvB-like protein 2 (Ruvbl2) antibody
RuvB-like AAA ATPase 2 (Ruvbl2) antibody
RuvB-like AAA ATPase 2 (ruvbl2) antibody
RuvB-like protein 2 (ruvbl2) antibody
RuvB like AAA ATPase 2 L homeolog (ruvbl2.L) antibody
RuvB like AAA ATPase 2 (ruvbl2) antibody
ruvB-like 2 (LOC726816) antibody
TATA box-binding protein (HBUT_RS02095) antibody
ruvb-like 2 (HAN_2g314) antibody
ruvB-like 2 (LOC100282179) antibody
ruvB-like 2 (LOC100284260) antibody
RuvB like AAA ATPase 2 (Ruvbl2) antibody
ruvB-like helicase 2 (LOC5573243) antibody

AAEL010341 antibody
cgi-46 antibody
ecp51 antibody
INO80J antibody
MGC52995 antibody
MGC69398 antibody
mp47 antibody
p47 antibody
rept antibody
Reptin antibody
RUVBL2 antibody
rvb2 antibody
TIH2 antibody
tip48 antibody
tip49b antibody
wu:fi25f01 antibody
xReptin antibody
zreptin antibody

Protein level used designations for RUVBL2

, , , , , , , , , , , , , , , , , , , , , 48 kDa TATA box-binding protein-interacting protein 48 kDa TBP-interacting protein 51 kDa erythrocyte cytosolic protein ECP-51 INO80 complex subunit J RuvB (E coli homolog)-like 2 TAP54-beta TIP60-associated protein 54-beta erythrocyte cytosolic protein, 51-KD repressing pontin 52 reptin52 protein ruvB-like 2 reptin RuvB-like protein 2 liebeskummer lik RuvB-like 2 RuvB-like 2 (E. coli) ruvB-like 2-like ruvb-like 2 RUVB2_AEDAE ruvB-like helicase 2

GENE ID	SPECIES
10856	Homo sapiens
20174	Mus musculus
292907	Rattus norvegicus
317678	Danio rerio
380092	Xenopus laevis
398205	Xenopus laevis
448144	Xenopus (Silurana) tropicalis
468949	Pan troglodytes
476418	Canis lupus familiaris
511048	Bos taurus
100355427	Oryctolagus cuniculus
100406934	Callithrix jacchus
100428794	Macaca mulatta
100451813	Pongo abelii
726816	Apis mellifera
4782276	Hyperthermus butylicus DSM 5456
5739660	Hemiselmis andersenii
100282179	Zea mays
100284260	Zea mays
100592111	Nomascus leucogenys
100730162	Cavia porcellus
5573243	Aedes aegypti

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Show all anti-RuvB-Like 2 (E. Coli) (RUVBL2) Antibodies with Pubmed References