TFF3 Proteins
(Trefoil Factor 3 (Intestinal) (TFF3))
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008].
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TFF3
Origin: Mouse
Host: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
TFF3
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
Latest Publications for our TFF3 Proteins
: "Nucleotide-mediated SPDEF modulates TFF3-mediated wound healing and intestinal barrier function during the weaning process." in: Scientific reports, Vol. 8, Issue 1, pp. 4827, (2018) (PubMed).: "Circulating serum trefoil factor 3 (TFF3) is dramatically increased in chronic kidney disease." in: PLoS ONE, Vol. 8, Issue 11, pp. e80271, (2013) (PubMed).
: "Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia." in: American journal of physiology. Heart and circulatory physiology, Vol. 303, Issue 12, pp. H1446-58, (2012) (PubMed).
: "Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach." in: Journal of proteome research, Vol. 9, Issue 1, pp. 545-55, (2010) (PubMed).
: "Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas." in: British journal of cancer, Vol. 99, Issue 5, pp. 768-73, (2008) (PubMed).
: "Identification and use of the putative Bacteroides ovatus xylanase promoter for the inducible production of recombinant human proteins." in: Microbiology (Reading, England), Vol. 154, Issue Pt 10, pp. 3165-74, (2008) (PubMed).
Aliases for TFF3 Proteins
trefoil factor 3 (TFF3) Proteinstrefoil factor 3, intestinal (Tff3) Proteins
trefoil factor 3 (Tff3) Proteins
ITF Proteins
mITF Proteins
P1B Proteins
TFF3 Proteins
TFI Proteins
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