Protein Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with ATP1A4

• ATPase Na+/K+ transporting subunit alpha 4 (ATP1A4) antibody
• ATPase, Na+/K+ transporting, alpha 4 polypeptide (Atp1a4) antibody
• ATPase Na+/K+ transporting subunit alpha 4 (Atp1a4) antibody

• ATP1A1 antibody
• ATP1AL2 antibody

Protein level used designations for ATP1A4

ATPase, Na+/K+ transporting, alpha polypeptide-like 2 , Na(+)/K(+) ATPase alpha-4 subunit , Na+/K+ ATPase 4 , Na+/K+ ATPase, alpha-D polypeptide , Na,K-ATPase subunit alpha-C , sodium pump 4 , sodium pump subunit alpha-4 , sodium-potassium ATPase catalytic subunit alpha-4 , sodium/potassium-transporting ATPase alpha-4 chain , sodium/potassium-transporting ATPase subunit alpha-4 , Na+/K+ ATPase alpha 4 subunit