PTPN1 Proteins
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Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (Active) Protein Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-435) protein (His tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-432) protein (His tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-321) Protein Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-435) protein (GST tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 322-406) protein (GST tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) protein (DYKDDDDK Tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 2-321) (Active) protein (His tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) protein (Myc-DYKDDDDK Tag) Protein
Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) protein (His tag) Protein
PTPN1 Protein Profile
Protein Summary
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
Alternative names and synonyms associated with PTPN1
- protein tyrosine phosphatase, non-receptor type 1 (PTPN1) antibody
- protein tyrosine phosphatase, non-receptor type 1 (Ptpn1) antibody
- protein tyrosine phosphatase, non-receptor type 1 (ptpn1) antibody
- protein tyrosine phosphatase, non-receptor type 1 L homeolog (ptpn1.L) antibody
- CPTP1 antibody
- Ptp antibody
- PTP-1B antibody
- PTP-HA2 antibody
- ptp1b antibody
- PTPN1 antibody
- wu:fk54h03 antibody
Protein level used designations for PTPN1
protein tyrosine phosphatase, non-receptor type 1 , tyrosine-protein phosphatase non-receptor type 1 , tyrosine-protein phosphatase non-receptor type 1-like , protein tyrosine phosphatase, placental , protein-tyrosine phosphatase 1B , protein-protein-tyrosine phosphatase HA2 , protein-tyrosine phosphatase HA2 , PTP-1B , fk54h03 , protein tyrosine phosphatase 1b , non-receptor protein tyrosine phosphatase , phosphoprotein phosphatase , tyrosine phosphatase 1B
| GENE ID | SPECIES |
|---|---|
| 469970 | Pan troglodytes |
| 702016 | Macaca mulatta |
| 100172151 | Pongo abelii |
| 100354834 | Oryctolagus cuniculus |
| 100387823 | Callithrix jacchus |
| 100481720 | Ailuropoda melanoleuca |
| 5770 | Homo sapiens |
| 19246 | Mus musculus |
| 24697 | Rattus norvegicus |
| 30081 | Danio rerio |
| 444514 | Xenopus laevis |
| 395688 | Gallus gallus |
| 477263 | Canis lupus familiaris |
| 396667 | Sus scrofa |
| 508658 | Bos taurus |
Did you look for something else?
- Protein Tyrosine Phosphatase, Mitochondrial 1 Proteins
- Protein tyrosine Phosphatase-Like A Domain Containing 1 Proteins
- Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member B Proteins
- Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A Proteins
- Protein Tyrosine Phosphatase Type IVA, Member 3 Proteins
- Protein tyrosine Phosphatase Type IVA, Member 2 Proteins
- Protein Tyrosine Phosphatase Type IVA, Member 1 Proteins
- Protein Tyrosine Phosphatase Receptor Type K Proteins
- Protein Tyrosine Phosphatase Receptor Type F Proteins
- Protein Tyrosine Phosphatase G1 Proteins
- Protein Tyrosine Phosphatase F Interacting Protein 1 Proteins
- Protein Tyrosine Phosphatase Domain Containing 1 Proteins
- Protein Translation Factor SUI1 Homolog Proteins
- Protein Tob1 Proteins
- Protein Serine Kinase H1 Proteins
- Protein S Proteins
- Protein Regulator of Cytokinesis 1 Proteins
- Protein Quaking Proteins
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L Proteins
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1K Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 11 Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 14 Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 2 Proteins
- Protein Tyrosine Phosphatase, Non-Receptor Type 20B Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 21 Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 3 Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 7 Proteins
- Protein tyrosine Phosphatase, Non-Receptor Type 9 Proteins
- Protein tyrosine Phosphatase, Receptor Type, A Proteins
- Protein tyrosine Phosphatase, Receptor Type, B Proteins
- Protein tyrosine Phosphatase, Receptor Type, C Proteins
- Protein tyrosine Phosphatase, Receptor Type, D Proteins
- Protein tyrosine Phosphatase, Receptor Type, E Proteins
- Protein tyrosine Phosphatase, Receptor Type, F Polypeptide (PTPRF), Interacting Protein (Liprin), alpha 3 Proteins
- Protein tyrosine Phosphatase, Receptor Type, F Polypeptide (PTPRF), Interacting Protein (Liprin), alpha 4 Proteins
- Protein tyrosine Phosphatase, Receptor Type, G Proteins
- Protein tyrosine Phosphatase, Receptor Type, H Proteins
