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anti-Human TNFAIP3 Antibodies:
anti-Mouse (Murine) TNFAIP3 Antibodies:
anti-Rat (Rattus) TNFAIP3 Antibodies:
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Human Monoclonal TNFAIP3 Primary Antibody for CyTOF, FACS - ABIN4277015
Kupfner, Arcaroli, Yum, Nadler, Yang, Abraham: Role of NF-kappaB in endotoxemia-induced alterations of lung neutrophil apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 38 Pubmed References
The data demonstrate that miR (show MLXIP Antibodies)-125b regulates nasopharyngeal carcinoma cell proliferation and apoptosis by targeting A20/NF-kappaB (show NFKB1 Antibodies) signaling pathway, and miR (show MLXIP Antibodies)-125b acts as oncogene (show RAB1A Antibodies), whereas A20 functions as tumor suppressor.
we demonstrate that a pathological reduction in TNFAIP3 levels induced NF-kappaB (show NFKB1 Antibodies)/SMAD7 (show SMAD7 Antibodies) pathway activation, causing a deficiency in MSCs in ITP (show ITPA Antibodies) patients. The ability of ITP (show ITPA Antibodies)-MSCs to support megakaryocytic differentiation and thrombopoiesis of CD34 (show CD34 Antibodies)(+) cells was impaired.
miR (show MLXIP Antibodies)-125b regulates differentiation and reprogramming of T cell glucose metabolism via targeting A20 in T cell acute lymphoblastic leukemia.
Review/Meta-analysis: TNFAIP3 gene rs10499194, rs13207033 polymorphisms decrease the risk of rheumatoid arthritis, especially among Caucasian populations.
In vitro deletion of A20 in B cells compromised the expression of IL10.
Low A20 expression is associated with hepatocellular carcinoma.
The results suggest that TNFAIP3 polymorphisms (rs2230926, rs5029937, rs5029939, and rs3757173) are associated with susceptibility to systemic lupus erythematosus. (Meta-analysis)
Hepatitis C virus core protein ligates gC1qR (show C1QBP Antibodies) to induce A20 expression in macrophages via P38 (show CRK Antibodies), JNK (show MAPK8 Antibodies) and NF-kappaB (show NFKB1 Antibodies) signaling pathways, which leads to a low-grade chronic inflammation during HCV infection.
Results show that TNFAIP3 expression is regulated by miR (show MLXIP Antibodies)-19b through targeting its 3'-UTR (show UTS2R Antibodies) which contributes to the radioresistance of nasopharyngeal carcinoma and consequently activating the NF-kappaB (show NFKB1 Antibodies) pathway.
demonstrates that TNFAIP3 gene polymorphisms (rs2230926 and rs5029937) are associated with the increased risk of rheumatoid arthritis. [META-ANALYSIS]
Mice with A20 deficient B cells are prone to food allergy.
Tnfaip3, an anti-inflammatory gene, is located precisely underneath the linkage peak and contains two non-synonymous SNPs leading to conservative amino acid substitutions.
These results suggest that Leishmania exploits A20 and UCP2 (show UCP2 Antibodies) to impair inflammasome activation for disease propagation
A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1 (show SNAI1 Antibodies).
holding thymic production of natural Treg cells in check, A20 integrates Treg cell activity and increased effector T cell survival into an efficient CD4 (show CD4 Antibodies)(+) T cell response
these studies establish A20 as a crucial hepatoprotective factor.
These results suggested that A20 is involved in regulating intracerebral hemorrhage-induced inflammatory injury in both the central and peripheral system
the ubiquitin-modifying enzyme TNFAIP3/A20, an upstream regulator of T cell receptor (TCR) signaling in T cells, is an essential cell-intrinsic regulator of Natural killer T differentiation.
Data show the characterization and deduced amino acid sequence analysis for A20 gene which expression increases in MDBK cells infected by BVDV-1. Also, regulatory regions for NF-kappaB (show NFKB1 Antibodies) and Sp-1 (show SP1 Antibodies) additionally to an ARE element for mRNA stability were detected
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
tumor necrosis factor, alpha-induced protein 3
, OTU domain-containing protein 7C
, TNF alpha-induced protein 3
, putative DNA-binding protein A20
, tumor necrosis factor alpha-induced protein 3
, tumor necrosis factor inducible protein A20
, zinc finger protein A20
, tumor necrosis factor induced protein 3