TNR1A Protein (AA 31-210) (GST tag)
Recombinant TNR1A protein expressed in Escherichia coli (E. coli).
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Catalog No. ABIN5712514
Quick Overview for TNR1A Protein (AA 31-210) (GST tag) (ABIN5712514)
Target
TNR1A
(Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
Protein Type
Recombinant
Origin
Human
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
Purity
> 90 %
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Protein Characteristics
- AA 31-210
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Purification tag / Conjugate
- This TNR1A protein is labelled with GST tag.
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Sequence
- VPHLGDREKR DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE NVKGTEDSGT
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Purification
- SDS-PAGE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- TNR1A (Tumor Necrosis Factor Receptor Superfamily Member 1A (TNR1A))
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Alternative Name
- TNR1A
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Background
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
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Molecular Weight
- 47.6 kDa
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UniProt
- P19438
Target
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