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Human Monoclonal HEY1 Primary Antibody for IF, ELISA - ABIN525186
Tsuru, Setoguchi, Matsunoshita, Nagao-Kitamoto, Nagano, Yokouchi, Maeda, Ishidou, Yamamoto, Komiya: Hairy/enhancer-of-split related with YRPW motif protein 1 promotes osteosarcoma metastasis via matrix metallopeptidase 9 expression. in British journal of cancer 2015
Human Monoclonal HEY1 Primary Antibody for ELISA, WB - ABIN525187
Huang, Chu, Ye, Chen: Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum. in The Journal of biological chemistry 2014
Cow (Bovine) Polyclonal HEY1 Primary Antibody for IHC, WB - ABIN2779686
Meng, Su, Liu, Wang, Wang: Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2. in Neuroscience 2015
Simulation of HEY1 Ser (show SIGLEC1 Antibodies)-68 phosphorylation prevents its interaction with p53 (show TP53 Antibodies), RPL11 (show RPL11 Antibodies) and MDM2 (show MDM2 Antibodies) and abolishes HEY1 migration to nucleolar caps (show CAPS Antibodies) upon ribosomal stress. Our findings uncover a novel mechanism for cross-talk between Notch (show NOTCH1 Antibodies) signalling and nucleolar stress
Pancreatic involvement occurs in mesenchymal chondrosarcoma harboring the HEY1-NCOA2 (show NCOA2 Antibodies) gene fusion.
HGF (show HGF Antibodies)-induced FRA1 (show FOSL1 Antibodies) activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.
Expression of Hey1 induces translocation of FBXO45 (show FBXO45 Antibodies) into the nucleus.
Overexpression of HEY1 and HEY2 (show HEY2 Antibodies) in esophageal squamous cell carcinoma (ESCC) is correlated to different indices of poor prognosis, and it is extrapolated that such overexpression is important in progression and development of ESCC tumorigenesis.
bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 and Hey2 (show HEY2 Antibodies) gene expression within the first few hours after medium change
PML (show PML Antibodies) degradation mechanism through Notch (show NOTCH1 Antibodies)/Hey1-induced repression of the PML (show PML Antibodies) deubiquitinase USP11 (show USP11 Antibodies) involved in brain tumour pathogenesis
MMP9 (show MMP9 Antibodies) was a downstream effector of HEY1 that promotes the invasion of osteosarcoma cells. Knockdown of HEY1 decreased the expression of MMP9 (show MMP9 Antibodies).
In prostate tumors, the overexpression of PTOV1 (show PTOV1 Antibodies) was associated with decreased expression of HEY1 and HES1 (show HES1 Antibodies), and this correlation was significant in metastatic lesions.
a new HRD1 (show SYVN1 Antibodies)-associated membrane protein named HERP2, which is homologous to the previously identified HRD1 (show SYVN1 Antibodies) partner HERP1 (show HEY2 Antibodies). Despite sequence homology, HERP2 is constitutively expressed in cells, whereas HERP1 (show HEY2 Antibodies) is highly induced by ER stress.
A Jagged1 (show JAG1 Antibodies)-Hey1 signal might mediate the impairment of angiogenesis induced by Ang II (show AGT Antibodies) during cardiac hypertrophy.
Cyclic stretch enhanced the BMP-2induced osteoblastic differentiation through the inhibition of Hey1.
Hes (show ATCAY Antibodies)/Hey signaling at the Atoh1 (show ATOH1 Antibodies) promoter has a role in selection of cell fate in the organ of Corti
These in vitro and in vivo data support an anti-adipogenic role of COUP-TFII (show NR2F2 Antibodies) via downregulating the Notch (show NOTCH1 Antibodies) signaling target gene Hey1.
Hey proteins mechanistically repress target genes via histone deacetylase (show HDAC1 Antibodies) recruitment and histone deacetylation.
Hey1 and Hey2 (show HEY2 Antibodies) in endothelial cells play important roles in vascular development.
findings indicate that Hey1 and Hey2 (show HEY2 Antibodies) control the spatial and temporal pattern of auditory HC differentiation.
This study demonistrated that demonstrates that the lack of Hesr1 leads to an alteration in sensitivity to dopamine accompanied by enhanced prepulse inhibition.
A muscle-specific (show EIF3K Antibodies) regulatory element of p57(kip2 (show CDKN1C Antibodies)) directly activated by muscle regulatory factors in myoblasts but repressed by the Notch (show NOTCH1 Antibodies) targets Hes1 (show HES1 Antibodies)/Hey1 in progenitor cells, is identified.
Notch (show NOTCH1 Antibodies)-RBPjk (show RBPJ Antibodies) signaling functions in part through Hey1-mediated inhibition of NFATc1 (show NFATC1 Antibodies) to suppress osteoblastogenesis, contributing to bone homeostasis in vivo
abrogation of Hey1 function in adult pallial Neural stem cells in vivo, including quiescent Neural stem cells, leads to their differentiation without affecting their proliferation state.
Expression of seven hairy/E(spl (show SGPL1 Antibodies)) (her) genes is reported in three neurogenic areas of the adult zebrafish brain (telencephalon, hypothalamus, and midbrain) in relation to radial glia, proliferation, and neurogenesis.
hey1 represents a target of Delta-Notch (show NOTCH1 Antibodies) signaling dynamically expressed during somite formation in zebrafish
Results suggest that the negative regulatory loops between BMP/Tbx2 (show TBX2 Antibodies) and Gremlin (show GREM1 Antibodies) or Hey1 are responsible for defining the territory of the pronephric nephron.
HRT1 encodes a bhlh domain motif, a transcription repressor, which acts as an extended dimerization domain that contributes to the selection of partners.
XHRT1 plays an important role in glomerular development and early proximodistal patterning. [Xenopus HRT1]
This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
HES-related repressor protein 1
, HES-related repressor protein 2
, basic helix-loop-helix protein OAF1
, cardiovascular helix-loop-helix factor 2
, class B basic helix-loop-helix protein 31
, hairy and enhancer of split-related protein 1
, hairy-related transcription factor 1
, hairy/enhancer-of-split related with YRPW motif protein 1
, bHLH protein Hesr-1/Hey1
, cardiovascular basic helix-loop-helix factor 2
, Hairy/E(spl)-related with YRPW motif 1
, basic helix-loop-helix transcription factor
, protein xbc8