HEY1 antibody (C-Term)

Catalog No. ABIN2779686

There is 1 publication for this product available. The Rabbit Polyclonal anti-HEY1 antibody is suitable to detect HEY1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. It has been validated for WB and IHC.

Quick Overview for HEY1 antibody (C-Term) (ABIN2779686)

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEY1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HEY1 Antibody

Binding Specificity: C-Term

Purpose: HEY1 Antibody - C-terminal region

Sequence: PQNGHGNAGT TASPTEPHHQ GRLGSAHPEA PALRAPPSGS FGPVLPVVTS

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HEY1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HEY1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32512-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-HEY1 antibody (ABIN2779686)

Meng, Su, Liu, Wang, Wang: "Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2." in: Neuroscience, Vol. 306, pp. 100-14, (2015) (PubMed).

Target Details for HEY1

Target: HEY1 (Ha-Ry/enhancer-of-Split Related with YRPW Motif 1 (HEY1))

Alternative Name: HEY1

Background:

Background Information: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates.

Alternative Symbols: CHF2, OAF1, HERP2, HESR1, HRT-1, NERP2, hHRT1, BHLHb31

Protein Name: Hairy/enhancer-of-split related with YRPW motif protein 1

Molecular Weight: 33 kDa

Gene ID: 23462

NCBI Accession: NP_036390

UniProt: Q9Y5J3

Pathways: Tube Formation