VAMP1/VAMP2 antibody
This anti-VAMP1/VAMP2 antibody is a Mouse Monoclonal antibody detecting VAMP1/VAMP2 in IHC (p). Suitable for Human.
Catalog No. ABIN306588
Quick Overview for VAMP1/VAMP2 antibody (ABIN306588)
Target
VAMP1/VAMP2
(Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Cross-Reactivity
- Human
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Cross-Reactivity (Details)
- Human, cattle
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Characteristics
- Sheep anti vesicle associated membrane protein 1 and 2, VAMP 1 and 2, VAMP1/2, VAMP 1/2, VAMP-1/2, Synaptobrevin 1 and 2,The MOC-1 antibody belongs to cluster 1 antibodies which react with neuroendocrine tissue (N-CAM) and in the lung typically detect SCLC and carcinoids. On the VI. International Workshop on Leukocyte Differentiation (Kobe 1996) this antibody has been designed as CD56, which is a known marker for natural killer cells (NK-cells). Lung cancer is a heterogeneous disease which may be characterized by five histopathological criteria. A distinction is drawn between squamous epithelial carcinoma, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and small cell lung carcinoma (SCLC). The first four in this line are cited as "non-SCLC" in literature. A number of antibodies have been used for the characterization and clustering of lung carcinoma during the 1. International Workshop on Small Cell Lung Cancer Antigens, London 1987. Cluster 1 membrane protein 125 - 145 kDa.
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Immunogen
- Preparation of a SCLC-derived cell line
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Isotype
- IgG
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Application Notes
- Heat pre-treatment of formalin-fixed tissue with Unmasking Fluid C or G,IHC(P),60 min at RT,(RTU) neat
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Restrictions
- For Research Use only
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Buffer
- Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 30 immunohistochemical tests (100 μL working solution / test). Use appropriate antibody diluent if required.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C
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- VAMP1/VAMP2 (Vesicle-Associated Membrane Protein 1/2 (Synaptobrevin 1/2) (VAMP1/VAMP2))
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Alternative Name
- Vesicle Associated Membrane Protein (VAMP 1/2)
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UniProt
- P13591
Target
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